Effectiveness of Narval CC™ device in the treatment of obstructive sleep apnea.

Q1 Medicine Sleep Medicine: X Pub Date : 2023-06-12 eCollection Date: 2023-12-15 DOI:10.1016/j.sleepx.2023.100076
Johan H Therchilsen, Poul Kirketerp, Preben Homoe
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Abstract

Mandibular advancement devices (MAD) are used in sleep apnea with varying results. We aimed to examine whether or not a MAD should be an integral treatment modality in the care of our patients with obstructive sleep apnea. We designed a feasibility study and included 32 patients after meeting inclusion criteria. Only 3 patients did not finish the second sleep study exam. The intervention was an individually designed MAD and a sleep study exam was performed prior and post treatment. The outcome objective was an apnea-hypopnea index of under 10 and with a 50% reduction. Patient population had a baseline AHI of 19.0 and mean reduction of AHI with MAD treatment to 13.3 yielding a MAD efficacy rate of 31% when outcome objectives were applied. The average reduction in AHI was 24.8% with 9 of the 29 patients actually experiencing an increase in AHI with MAD treatment. When there was a reduction in AHI using the MAD device the AHI reduction rate was 49.1% and there was a tendency for better treatment outcome when apnea-hypopnea was predominantly supine. A mandibular advancement device serves as an important treatment modality in the care of patients with obstructive sleep apnea due to patient satisfaction and compliance. The broad range of treatment response to our MAD device highlights the importance of performing a sleep study exam after initiation of treatment with a MAD but also illustrates the complexity and need for individually tailored treatment for patients with obstructive sleep apnea.

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Narval CC™ 设备治疗阻塞性睡眠呼吸暂停的效果。
下颌前突矫正器(MAD)被用于治疗睡眠呼吸暂停,但效果各不相同。我们的目的是研究 MAD 是否应该成为阻塞性睡眠呼吸暂停患者治疗过程中不可或缺的治疗方式。我们设计了一项可行性研究,纳入了 32 名符合纳入标准的患者。只有 3 名患者没有完成第二次睡眠检查。干预措施是单独设计的 MAD,治疗前后都进行了睡眠检查。结果目标是呼吸暂停-低通气指数低于 10 且降低 50%。患者的基线 AHI 为 19.0,经 MAD 治疗后,AHI 平均降低至 13.3,因此,当应用结果目标时,MAD 的有效率为 31%。AHI 的平均降低率为 24.8%,29 名患者中有 9 人在接受 MAD 治疗后 AHI 实际有所升高。当使用 MAD 设备降低 AHI 时,AHI 降低率为 49.1%,当呼吸暂停-低通气以仰卧位为主时,治疗效果更佳。下颌前突矫正器是治疗阻塞性睡眠呼吸暂停患者的一种重要方法,患者满意度高,依从性好。我们的下颌前突矫正器的治疗反应范围很广,这凸显了在开始使用下颌前突矫正器治疗后进行睡眠研究检查的重要性,同时也说明了阻塞性睡眠呼吸暂停患者个性化治疗的复杂性和必要性。
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来源期刊
Sleep Medicine: X
Sleep Medicine: X Medicine-Medicine (all)
CiteScore
4.00
自引率
0.00%
发文量
17
审稿时长
25 weeks
期刊最新文献
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