Relación circunferencia abdominal e insulinorresistencia y su impacto en parámetros seminales

Abstract

Infertility affects between 8-15% of general population of reproductive age. The term refers to the inability of couples to achieve pregnancy after one year of unprotected sexual activity. The male factor is solely responsible in 20%, and 30-40% with the couple.

The initial evaluation of the male reproductive situation is the seminogram, which is considered as a key assessment tool.

Several conditions may be associated with infertility in men, such as endocrine-metabolic diseases such as hypogonadism, hyperprolactinaemia, dysthyroidism, dyslipidaemia, alterations glucose and insulin alteration, central obesity, or to the group of parameters called metabolic syndrome (MS). Obesity contributes to development of hypertension, dyslipidaemia and insulin resistance.

The aim of our review was to find documents that showed the impact of the association between waist circumference and insulin resistance in semen parameters as a possible origin of male infertility. The search for information was conducted in Medline, ScienceDirect, and Scopus. The terms used for the basic search were: obesity, abdominal circumference, insulin resistance, male infertility, semen, semen parameters.

There are studies documenting the deleterious effect of obesity and insulin resistance in female fertility. Some performed in men suggest harmful effects on their reproductive potential.

Semen anomalies are found in obese men with insulin resistance, but still require further studied to assess the association between them. The literature reports semen anomalies associated with obesity that are still to be elucidated.