Incidence of arrhythmias during air transportation following intravenous streptokinase therapy

MD, FACEP B.J. Ringenberg , MD D. Wysham , MD, FACC C.W. White , MS K.R. Stults , MD, FACC M.A. Kienzle
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Abstract

Patients receiving intravenous streptokinase (IV-STK) during acute myocardial infarction (AMI) may be at risk for arrhythmias complicating aeromedical transportation to a tertiary care center.

A brief report of forty adult patients prospectively studied during helicopter transport utilizing continuous ambulatory electrocardiography (Holter monitor) to determine the incidence and severity of cardiac arrhythmias is presented. Patients with AMI treated with IV-STK were compared to patients with a variety of other cardiac and non-cardiac conditions transported by air. Although high grade ventricular arrhythmias were more common in the patients receiving IV-STK, no patient experienced symptomatic arrhythmias requiring defibrillation or cardioversion. The arrhythmias recorded did not correlate with clinical reperfusion of the infarct related vessel. We conclude that aeromedical transport of patients with AMI treated with IV-STK can be accomplished safely.

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静脉链激酶治疗后空运中心律失常的发生率
急性心肌梗死(AMI)期间接受静脉注射链激酶(IV-STK)治疗的患者可能存在心律失常的风险,并发送到三级医疗中心的航空运输。简要报告了40名成年患者在直升机运输期间前瞻性研究,利用连续动态心电图(霍尔特监测仪)来确定心律失常的发生率和严重程度。将经IV-STK治疗的AMI患者与空运的其他各种心脏和非心脏疾病患者进行比较。虽然高度室性心律失常在IV-STK患者中更为常见,但没有患者出现需要除颤或复律的症状性心律失常。记录的心律失常与梗死相关血管的临床再灌注无关。我们的结论是,IV-STK治疗的AMI患者的航空医疗运输是可以安全完成的。
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