Maternal BMI in the preconception period, and association with child zBMI growth rates

IF 2.7 3区医学 Q1 PEDIATRICS Pediatric Obesity Pub Date : 2022-12-27 DOI:10.1111/ijpo.12999

Arin C. Deveci, Charles D. G. Keown-Stoneman, Jonathon L. Maguire, Deborah L. O'Connor, Laura N. Anderson, Cindy-Lee Dennis, Catherine S. Birken, for the TARGet Kids! Collaboration

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引用次数: 2

Abstract

Background

Elevated body mass index (BMI) and rapid growth in early childhood are important predictors of obesity risk. The association between maternal preconception BMI and child growth rates is unclear.

Objectives

To assess the association between measured maternal preconception BMI and child age- and sex- standardized WHO BMI z-score (zBMI) growth rates and mean zBMI, in children aged 0–10 years old.

Methods

A longitudinal cohort study was conducted with children (n = 499) enrolled in The Applied Research Group for Kids (TARGet Kids!) primary care practice-based research cohort. Maternal BMI was measured during the preconception period, defined as the 2 years prior to pregnancy. Repeated measures of child weight and height were obtained between 0 and 10 years of age. Linear mixed models were used to evaluate the association between maternal BMI and child zBMI growth rates and mean zBMI.

Results

Maternal preconception BMI was associated with child zBMI growth rate during some growth periods, with the strongest association from age 0 to 4 months; a 5 kg/m2 higher maternal BMI was associated with 0.031 zBMI SD unit/mo higher growth rate (p = 0.004), and 0.186 SD unit higher mean child zBMI (p = 0.0002).

Conclusions

Maternal preconception BMI was associated with growth rate and mean zBMI in early childhood. The preconception period may be an important target for health interventions to promote healthy child growth rate and weight outcomes.

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孕前母亲BMI与儿童zBMI增长率的关系

背景:儿童早期体重指数(BMI)升高和快速生长是肥胖风险的重要预测因素。孕妇孕前体重指数与儿童生长速率之间的关系尚不清楚。目的评估0-10岁儿童孕前BMI测量值与儿童年龄和性别标准化WHO BMI z-score (zBMI)增长率和平均zBMI之间的关系。方法采用纵向队列研究，纳入儿童应用研究小组(目标儿童!)初级保健实践研究队列的儿童(n = 499)。在孕前期间测量母亲的BMI，定义为怀孕前2年。在0岁至10岁之间反复测量儿童体重和身高。采用线性混合模型评估母亲BMI与儿童zBMI增长率和平均zBMI之间的关系。结果母亲孕前BMI在某些生长期与儿童zBMI生长速率相关，其中0 ~ 4月龄相关性最强;母亲体重指数每高5 kg/m2，其生长率提高0.031 zBMI SD单位/月(p = 0.004)，儿童平均体重指数提高0.186 SD单位(p = 0.0002)。结论母亲孕前BMI与儿童早期生长速率和平均zBMI相关。孕前期可能是健康干预措施的一个重要目标，以促进健康的儿童生长速度和体重结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatric Obesity PEDIATRICS-

CiteScore

7.30

自引率

5.30%

发文量

117

审稿时长

6-12 weeks

期刊介绍： Pediatric Obesity is a peer-reviewed, monthly journal devoted to research into obesity during childhood and adolescence. The topic is currently at the centre of intense interest in the scientific community, and is of increasing concern to health policy-makers and the public at large. Pediatric Obesity has established itself as the leading journal for high quality papers in this field, including, but not limited to, the following: Genetic, molecular, biochemical and physiological aspects of obesity – basic, applied and clinical studies relating to mechanisms of the development of obesity throughout the life course and the consequent effects of obesity on health outcomes Metabolic consequences of child and adolescent obesity Epidemiological and population-based studies of child and adolescent overweight and obesity Measurement and diagnostic issues in assessing child and adolescent adiposity, physical activity and nutrition Clinical management of children and adolescents with obesity including studies of treatment and prevention Co-morbidities linked to child and adolescent obesity – mechanisms, assessment, and treatment Life-cycle factors eg familial, intrauterine and developmental aspects of child and adolescent obesity Nutrition security and the "double burden" of obesity and malnutrition Health promotion strategies around the issues of obesity, nutrition and physical activity in children and adolescents Community and public health measures to prevent overweight and obesity in children and adolescents.