Pediatric Obesity最新文献

Residential Neighbourhood Environments and Health Behaviours Among Children and Adolescents Initiating Obesity Management Care: Secondary Analyses of Data From the CANadian Paediatric Weight Management Registry (CANPWR) 开始肥胖管理护理的儿童和青少年的居住社区环境和健康行为：加拿大儿科体重管理登记处（CANPWR）数据的二次分析

IF 2.7 3区医学 Q1 PEDIATRICS

Pediatric Obesity

Pub Date : 2026-02-04 DOI: 10.1111/ijpo.70087

Yujia Tang, Sonia Semenic, Aurélie Baillot, Mylène Riva, Geoff D. C. Ball, Stasia Hadjiyannakis, Jill Hamilton, Josephine Ho, Laurent Legault, Ian Zenlea, Katherine M. Morrison, Andraea Van Hulst

Objective

Examine associations between neighbourhood characteristics and health behaviours (physical activity, screen time, sleep duration) in boys and girls initiating obesity management care across Canada.

Methods

We analysed cross-sectional data from the CANadian Paediatric Weight management Registry (2013–2017) for 803 participants (with overweight or obesity; 5–17 years old). Questionnaire-assessed health behaviours included total physical activity (PA), organised PA outside of school, screen time, and sleep duration. Total PA was classified as high vs. low based on current recommendations, organised PA as high vs. low based on average attained levels for Canadian children, and screen time and sleep duration as meeting vs. not meeting recommendations. Neighbourhood characteristics (walkability, greenness, material and social deprivation) were computed for the first three digits of residential postal codes. Covariate-adjusted associations were examined using generalised estimating equations stratified by sex.

Results

Participants (50% boys; mean ± SD: age, 11.9 ± 3.1 years; BMI z-score, 3.28 ± 1.06) living in low (vs. high) social deprivation neighbourhoods were more likely to engage in high total PA, particularly among boys (PR = 1.32, 95% CI: 1.01, 1.73). Boys living in neighbourhoods with high (vs. low) walkability (PR = 3.56, 95% CI: 1.97, 6.44) and higher greenness (PR = 1.72, 95% CI: 1.17, 2.64) were more likely to engage in high organised PA. Girls living in neighbourhoods with very low (vs. high) material deprivation were more likely to engage in high organised PA (PR = 4.17, 95% CI: 1.52, 11.45). No associations were found for screen time or sleep duration.

Conclusions

This study adds to the evidence linking neighbourhood environments to health behaviours in children and adolescents living with obesity and who are initiating obesity management care. Specifically, less social deprivation and greater walkability and greenness were associated with higher PA among boys, while less material deprivation was linked to higher PA among girls.

目的：研究加拿大各地发起肥胖管理护理的男孩和女孩的邻里特征与健康行为（身体活动、屏幕时间、睡眠时间）之间的关系。方法：我们分析了来自加拿大儿科体重管理登记处（2013-2017）的803名参与者（超重或肥胖；5-17岁）的横断面数据。问卷评估的健康行为包括总体力活动（PA）、校外有组织的PA、屏幕时间和睡眠时间。总PA根据目前的建议分为高与低，有组织PA根据加拿大儿童的平均达到水平分为高与低，屏幕时间和睡眠时间为符合与不符合建议。根据居民邮政编码的前三位数字计算了社区特征（可步行性、绿色、物质和社会剥夺）。用按性别分层的广义估计方程检验协变量调整的关联。结果：生活在低（高）社会剥夺社区的参与者（50%为男孩；平均±SD：年龄，11.9±3.1岁；BMI z-score, 3.28±1.06）更有可能从事高总PA，尤其是男孩（PR = 1.32, 95% CI: 1.01, 1.73）。生活在可步行性高（相对于低）社区（PR = 3.56, 95% CI: 1.97, 6.44）和绿色度高（PR = 1.72, 95% CI: 1.17, 2.64）的男孩更有可能参与高组织的PA。生活在物质匮乏程度非常低（相对较高）社区的女孩更有可能参与高度组织化的PA （PR = 4.17, 95% CI: 1.52, 11.45）。屏幕时间和睡眠时间没有关联。结论：本研究为社区环境与肥胖儿童和青少年健康行为之间的联系提供了新的证据，这些儿童和青少年正在接受肥胖管理护理。具体来说，较少的社会剥夺和更大的步行性和绿化与男孩的高PA相关，而较少的物质剥夺与女孩的高PA相关。

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引用次数: 0

Associations of Maternal Prenatal Inflammation With Child Adiposity: The Healthy Start Study. 母亲产前炎症与儿童肥胖的关系：健康开始研究。

IF 2.7 3区医学 Q1 PEDIATRICS

Pediatric Obesity

Pub Date : 2026-02-01 DOI: 10.1111/ijpo.70088

Makayla Moran, Kyle Salmon, Satvinder K Dhaliwal, Dana Dabelea, Wei Perng

Introduction: While inflammation is a normal physiological process of pregnancy, exposure to excess inflammation in utero may have unfavourable consequences for the offspring's health. This analysis investigated associations of prenatal inflammation with offspring adiposity in early childhood.

Methods: Among 555 mother-offspring pairs in the Healthy Start Study, we measured three inflammation biomarkers-C-reactive protein, interleukin-6 and tumour necrosis factor-α-at ~28 gestational weeks. We internally standardised each biomarker and took its average as an indicator of overall exposure to prenatal inflammation. When offspring were 4-6 years old, we measured weight and height for body mass index (BMI) z-score calculation; waist circumference; and % fat mass (%FM) using air displacement plethysmography. In the analysis, we used linear regression to examine associations of the prenatal inflammation z-score with offspring outcomes. As an exploratory analysis, we conducted stratified analysis by maternal race/ethnicity, which is known to modify associations in maternal-child health studies.

Results: After adjusting for offspring age and sex, each increment in the prenatal inflammation z-score corresponded with 0.31 (95% CI: 0.14, 0.48) higher BMI z-score, 1.43 (0.61, 2.25) cm higher waist circumference and 1.47 (0.43, 2.51) higher %FM in offspring. Further adjustment for maternal pre-pregnancy BMI attenuated estimates to the null for BMI z-score and waist circumference, but less for %FM (0.77 [-0.39, 1.94]; p = 0.19). These associations were driven by Hispanic mother-offspring pairs.

Conclusions: Prenatal inflammation may predispose offspring to greater adiposity during early childhood. This association is partially explained by maternal BMI and driven by participants of Hispanic ethnicity.

Trial registration: NCT #002273297.

虽然炎症是妊娠的正常生理过程，但在子宫内暴露于过度炎症可能对后代的健康产生不利后果。这项分析调查了产前炎症与儿童早期后代肥胖的关系。方法：在555对健康开始研究的母-子代中，我们在妊娠~28周测量了3种炎症生物标志物- c反应蛋白、白细胞介素-6和肿瘤坏死因子-α。我们对每个生物标志物进行了内部标准化，并将其平均值作为总体暴露于产前炎症的指标。当子代4-6岁时，测量体重和身高，计算体重指数（BMI） z分数；腰围;和%脂肪量（%FM）使用空气置换体积脉搏图。在分析中，我们使用线性回归来检验产前炎症z评分与后代结局的关系。作为一项探索性分析，我们根据母亲的种族/民族进行了分层分析，这在母婴健康研究中是已知的。结果：在调整后代年龄和性别后，产前炎症z-score每增加一次，后代BMI z-score增加0.31 (95% CI: 0.14, 0.48)，腰围增加1.43 (0.61,2.25)cm， FM %增加1.47（0.43,2.51）。进一步调整孕妇孕前BMI使BMI z-score和腰围的估计值降至零值，但对%FM的估计值较低（0.77 [-0.39,1.94];p = 0.19）。这些关联是由西班牙裔母亲和子女配对驱动的。结论：产前炎症可能使后代在儿童早期更容易肥胖。这种关联部分是由母亲的BMI解释的，并受到西班牙裔参与者的推动。试验注册：NCT #002273297。

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引用次数: 0

Household Food Insecurity Is Associated With Higher Adiposity Over Time Among Adolescents in Louisiana. 随着时间的推移，路易斯安那州青少年的家庭食品不安全与较高的肥胖有关。

IF 2.7 3区医学 Q1 PEDIATRICS

Pediatric Obesity

Pub Date : 2026-02-01 DOI: 10.1111/ijpo.70084

Ashley Fenton, Amanda E Staiano, Michael Celestin, Tekeda Ferguson, Candice A Myers, Tung-Sung Tseng, Stephanie T Broyles

Background: Few studies have examined how household food insecurity may impact longitudinal changes in adiposity among adolescents.

Objective: We investigated the link between household food insecurity and 2-year change in adolescent adiposity, with sex as a potential moderator.

Methods: Analyses included 222 adolescents living in and around Baton Rouge, Louisiana, who participated in the TIGER Kids study (baseline: June 2016-December 2017; follow-up: January 2018-August 2019). Household food security was measured using a validated two-question parent-reported survey. Adiposity outcomes were collected using anthropometry, dual-energy X-ray absorptiometry and abdominal magnetic resonance imaging (MRI). Multivariable multilevel models assessed associations between household food security and changes in adiposity.

Results: At baseline, the participants were 12.9 ± 1.9 years, 50.5% female, 37.4% non-White or Hispanic, 31.5% had obesity, and 11.3% were food insecure. Food-insecure adolescents exhibited significantly greater increases in BMI_p95 (b = 6.0% ± 2.2%, p = 0.0082), waist circumference (b = 4.1 ± 1.7 cm, p = 0.0158), total body fat percentage (b = 3.0% ± 1.3%, p = 0.0194) and visceral adipose tissue mass (b = 0.16 ± 0.06 kg, p = 0.0163), compared to their food-secure peers. The effect of food insecurity on adiposity did not differ between boys and girls.

Conclusions: This longitudinal study highlights the deleterious influence of food insecurity on adolescent adiposity. Efforts to alleviate food insecurity may play an important role in preventing obesity in adolescents.

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引用次数: 0

Early Determinants of Overweight and Obesity in Children Aged Under 2 Years in Mexico 墨西哥2岁以下儿童超重和肥胖的早期决定因素

IF 2.7 3区医学 Q1 PEDIATRICS

Pediatric Obesity

Pub Date : 2026-01-21 DOI: 10.1111/ijpo.70085

Lucía Hernández-Barrera, Belem Trejo-Valdivia, Danilo Castro-Sifuentes, Velia Margarita Cárdenas-Villarreal

Introduction

Obesity in infants is a growing problem in Mexico, affecting children's well-being and increasing long-term health risks. Evidence of the multilevel determinants during the first 1000 days is limited. This study aimed to examine the relationship between individual, maternal, household and the prevalence of overweight and obesity in children under 2 years of age.

Methods

A secondary analysis of the 2021 National Health and Nutrition Survey was conducted with a sample of 185 mother-infant binomials. To assess the combined prevalence of overweight and obesity (ow_ob) in infants, body mass index Z-scores were calculated by age and sex. By age group, multiple logistic regression models were adjusted to evaluate the association between childhood ow_ob and individual, maternal, household and place of residence variables.

Results

A combined prevalence of overweight and obesity of 29.7% was found. In infants aged 0–11 months, the highest probability of ow_ob (pr_ob = 0.87) was amongst infants of overweight mothers who worked outside the home. In infants aged 12–23 months, the highest likelihood of ow_ob (pr_ob = 0.885) was for children whose mothers had lower levels of education, were married, had a diagnosis of depression and experienced moderate or severe food insecurity.

Conclusions

This study is one of the first in Mexico to analyse multiple risk factors simultaneously at the national level, as it had a representative sample of children under 2 years old. The findings underscore the importance of early intervention and a comprehensive approach considering family and socioeconomic factors in childhood obesity prevention.

在墨西哥，婴儿肥胖是一个日益严重的问题，影响儿童的健康并增加长期健康风险。在前1000天内，多层次决定因素的证据有限。本研究旨在探讨个人、母亲、家庭与2岁以下儿童超重和肥胖患病率之间的关系。方法：对2021年全国健康与营养调查进行二次分析，样本为185名母婴。为了评估婴儿超重和肥胖（ow_ob）的联合患病率，体重指数z分数按年龄和性别计算。按年龄组调整多元logistic回归模型，评估儿童ow_ob与个体、母亲、家庭和居住地变量的相关性。结果：超重和肥胖的总患病率为29.7%。在0-11个月大的婴儿中，超重母亲外出工作的婴儿患ow_ob的概率最高（pr_ob = 0.87）。在12-23个月大的婴儿中，母亲受教育程度较低、已婚、被诊断为抑郁症、经历中度或重度食品不安全的儿童患ow_ob的可能性最高（pr_ob = 0.885）。结论：这项研究是墨西哥第一个在国家层面同时分析多种风险因素的研究之一，因为它有2岁以下儿童的代表性样本。研究结果强调了早期干预和综合考虑家庭和社会经济因素在儿童肥胖预防中的重要性。

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引用次数: 0

Socioeconomic Vulnerability and Its Associations With Dietary Patterns and Obesity Degree Among Children in Families Across Six European Countries: The Feel4Diabetes-Study 6个欧洲国家家庭儿童的社会经济脆弱性及其与饮食模式和肥胖程度的关系：感觉糖尿病研究

IF 2.7 3区医学 Q1 PEDIATRICS

Pediatric Obesity

Pub Date : 2026-01-20 DOI: 10.1111/ijpo.70072

Lubna Mahmood, Luis A. Moreno, Peter Schwarz, Lieven Annemans, Greet Cardon, Soukaina Hilal, Imre Rurik, Violeta Iotova, Natalya Usheva, Tsvetalina Tankova, Costas Anastasiou, Yannis Manios, Esther M. Gonzalez-Gil, the Feel4Diabetes-Study Group

Introduction

Previous studies suggest that children from lower socioeconomic status may be at higher risk of unhealthy eating. This study aims to examine the cumulative socioeconomic vulnerabilities and their association with dietary patterns and obesity levels in European children.

Methods

A total of 9664 parent-child dyads (79% mothers; 50.8% girls) from six European countries participated in the study. Families provided baseline information on energy balance-related behaviours and socioeconomic factors through questionnaires. Children's dietary habits were evaluated using semi-quantitative food frequency questionnaires, and anthropometric data were collected. Vulnerabilities were quantified through a composition of variables based on household income, parental education and employment. Multivariable and logistic regression analyses were performed.

Results

The study found significant associations between socioeconomic vulnerability and children's dietary habits and body mass index. Higher vulnerability was linked to a lower probability of fruit and vegetable intake, and a higher probability of consuming red meat, and energy-dense snacks. Children with the highest vulnerability had nearly four times higher odds of overweight/obesity (OR = 3.82, 95% CI: 3.05–4.76).

Conclusions

The findings of this study indicate that European children from families with a high socioeconomic vulnerability tend to have an unhealthy dietary profile and a higher degree of obesity. Therefore, public health programs should prioritise families facing high socioeconomic vulnerabilities promoting healthy eating to prevent childhood obesity at early stages.

Trial Registration

Clinical trials registry http://clinicaltrials.gov: NCT02393872

先前的研究表明，社会经济地位较低的儿童可能有更高的不健康饮食风险。本研究旨在研究欧洲儿童的累积社会经济脆弱性及其与饮食模式和肥胖水平的关系。方法：来自欧洲6个国家共9664对亲子对（79%为母亲，50.8%为女孩）参与研究。家庭通过问卷提供了与能量平衡相关的行为和社会经济因素的基线信息。采用半定量食物频率问卷对儿童的饮食习惯进行评估，并收集人体测量数据。脆弱性通过基于家庭收入、父母教育和就业的变量组合来量化。进行了多变量和逻辑回归分析。结果：研究发现社会经济脆弱性与儿童饮食习惯和体重指数之间存在显著关联。较高的脆弱性与摄入水果和蔬菜的可能性较低，以及食用红肉和高能量零食的可能性较高有关。最脆弱的儿童超重/肥胖的几率几乎是其他儿童的四倍（OR = 3.82, 95% CI: 3.05-4.76）。结论：本研究的结果表明，来自高社会经济脆弱性家庭的欧洲儿童往往有不健康的饮食习惯和更高程度的肥胖。因此，公共卫生计划应优先考虑面临高社会经济脆弱性的家庭，促进健康饮食，以预防儿童早期肥胖。临床试验注册：http://clinicaltrials.gov: NCT02393872。

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引用次数: 0

Correction to ‘30-Day Morbidity and Mortality of Bariatric Metabolic Surgery in Adolescence During the COVID-19 Pandemic—The GENEVA Study’ 对“2019冠状病毒病大流行期间青少年减肥代谢手术30天发病率和死亡率——日内瓦研究”的更正。

IF 2.7 3区医学 Q1 PEDIATRICS

Pediatric Obesity

Pub Date : 2026-01-15 DOI: 10.1111/ijpo.70086

R. Singhal, T. Wiggins, J. Super, et al., “30-Day Morbidity and Mortality of Bariatric Metabolic Surgery in Adolescence During the COVID-19 Pandemic—The GENEVA Study,” Pediatric Obesity 16, no. 12 (2021): e12832. https://doi.org/10.1111/ijpo.12832.

The first name of one of the collaborative authors was mistakenly misspelled. The correct full name of the author is ‘Ahmet Bozdag’.

We apologise for this error.

R. Singhal， T. Wiggins， J. Super，等，“2019冠状病毒病大流行期间青少年减肥代谢手术的30天发病率和死亡率-日内瓦研究”，《儿童肥胖》，第16期。12 (2021): e12832。https://doi.org/10.1111/ijpo.12832.The其中一位合作作者的名字被拼错了。作者的正确全名是“Ahmet Bozdag”。我们为这个错误道歉。

引用次数: 0

Longer Breastfeeding Is Associated With Healthier Body Mass Index Trajectories and Lower Risk of Overweight and Obesity in Youth Aged 9–12 Years 在9-12岁的青少年中，更长时间的母乳喂养与更健康的体重指数轨迹和更低的超重和肥胖风险相关

IF 2.7 3区医学 Q1 PEDIATRICS

Pediatric Obesity

Pub Date : 2026-01-07 DOI: 10.1111/ijpo.70082

Jonatan Ottino González, Miguel Angel Rivas Fernández, Sevan Esaian, Michael I. Goran, Shana Adise

Background

The association between breastfeeding and adolescent obesity remains unclear because most previous studies included youth with obesity. We explored these associations from ages 9 to 12 amongst initially healthy weight youth.

Methods

The analytic sample included 4161 youth (10 586 observations across three assessments; all healthy weight at baseline; 50.7% female; 52% breastfed more than 6 months) from the Adolescent Brain Cognitive Development (ABCD) Study. Linear mixed-effects models examined breastfeeding × age × sex and breastfeeding × puberty × sex interactions on BMI trajectories (kg/m²). Logistic regression estimated the risk of unhealthy weight (BMI ≥ 85th percentile) by ages 11–12. All analyses were stratified by sex.

Results

Three-way interactions were not significant. Significant breastfeeding × age interactions (β = −0.005, p < 0.001) indicated that breastfed youth exhibited lower BMI trajectories, particularly when breastfed for more than 6 months (β = −0.006, p < 0.001). Significant breastfeeding × puberty interactions showed lower BMI trajectories across pubertal stages amongst breastfed youth (β = −0.06, p = 0.017), observed only in boys and especially in those breastfed beyond 6 months (β = −0.11, p = 0.005). Breastfeeding was associated with a reduced unhealthy weight risk at ages 11–12 (RR = 0.78, p = 0.002), exclusively in boys and amongst those breastfed more than 6 months (RR = 0.52, p < 0.001). No associations were found in girls.

Conclusion

Amongst initially healthy weight youth, breastfeeding, especially beyond 6 months, was associated with healthier BMI trajectories and lower unhealthy weight risk in boys. Although these sex-specific patterns warrant further research, our findings suggest that the associations between breastfeeding and body weight development extend into adolescence.

背景：母乳喂养与青少年肥胖之间的关系尚不清楚，因为大多数先前的研究包括青少年肥胖。我们研究了9岁至12岁体重正常的青少年之间的这些联系。方法：分析样本包括来自青少年大脑认知发展（ABCD）研究的4161名青少年（3次评估共10586次观察结果；基线体重均为健康；50.7%为女性；52%母乳喂养超过6个月）。线性混合效应模型检验了母乳喂养×年龄×性别和母乳喂养×青春期×性别对BMI轨迹（kg/m2）的相互作用。Logistic回归估计11-12岁时体重不健康（BMI≥85百分位数）的风险。所有分析均按性别分层。结果：三向交互作用不显著。结论：在最初体重健康的青少年中，母乳喂养，尤其是6个月以上的男孩，与更健康的BMI轨迹和更低的不健康体重风险相关。尽管这些性别特异性模式值得进一步研究，但我们的研究结果表明，母乳喂养和体重发育之间的联系延伸到了青春期。

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引用次数: 0

Correction to ‘The Appetitive Responses to a Meal Are Not Affected by Its Carbohydrate Content in Adolescents With Obesity: A Pilot Study’ 更正“肥胖青少年对一餐的食欲反应不受其碳水化合物含量的影响：一项初步研究”。

IF 2.7 3区医学 Q1 PEDIATRICS

Pediatric Obesity

Pub Date : 2025-12-29 DOI: 10.1111/ijpo.70081

Z. Ghamdi, H. Moore, J. Siroux, et al., “The Appetitive Responses to a Meal Are Not Affected by Its Carbohydrate Content in Adolescents With Obesity: A Pilot Study,” Pediatric Obesity 21, no. 1 (2026): e70077, https://doi.org/10.1111/ijpo.70077.

In the author list, the first names and family names of the authors were inadvertently reversed. The correct author list is provided below:

‘Zainab Ghamdi, Halim Moore, Julie Siroux, Duane Beraud, Shaea Alkahtani, Abdullah F. Alghannam, Bruno Pereira, Julie Masurier, Graham Finlayson, Valérie Julian, Laurie Isacco, David Thivel’

The online version of the article has also been updated.

We apologise for this error.

Z. Ghamdi， H. Moore， J. Siroux等，“肥胖青少年对一餐的食欲反应不受其碳水化合物含量的影响：一项初步研究”，《儿童肥胖》21期，第2期。1 (2026): e70077, https://doi.org/10.1111/ijpo.70077.In作者名单中，作者的名字和姓氏被无意中颠倒了。正确的作者名单如下：“Zainab Ghamdi, Halim Moore, Julie Siroux, Duane Beraud, Shaea Alkahtani, Abdullah F. Alghannam, Bruno Pereira, Julie Masurier, Graham Finlayson, valsamrie Julian, Laurie Isacco, David Thivel”文章的在线版本也已更新。我们为这个错误道歉。

引用次数: 0

Starting Age for Screening Metabolic Dysfunction-Associated Steatotic Liver Disease in Children Using Controlled Attenuation Parameter on Transient Elastography 用瞬时弹性成像控制衰减参数筛选儿童代谢功能障碍相关脂肪变性肝病的起始年龄

IF 2.7 3区医学 Q1 PEDIATRICS

Pediatric Obesity

Pub Date : 2025-12-22 DOI: 10.1111/ijpo.70080

Li-Wen Lee, Jrhau Lung, Ju-Bei Yen, Chao-Yu Chen, Yu-San Liao

Background

Rising sedentary behaviour and consumption of sugar-sweetened beverages and ultra-processed foods have increased the risk and earlier onset of obesity in children.

Objectives

To define controlled attenuation parameter (CAP) cut-off values in healthy children, assess the prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) in children with overweight and obesity, and establish an appropriate starting age for MASLD screening in our population.

Methods

Healthy primary school children were recruited. Hepatic steatosis was assessed using CAP, and body composition data were collected during two periods: August 2020–March 2021 and February 2023–May 2024.

Results

Of 1653 participants (mean age 9.5 ± 1.7 years), 976 children with normal weight were used to establish reference intervals. Hepatic steatosis was defined as a CAP above 247 dB/m (97.5th percentile). The prevalences of MASLD in children with overweight and obesity were 0% and 16%, respectively, in school grade 1, which increased to 19% and 75% in school grade 6 (p < 0.001).

Conclusions

Screening for hepatic steatosis associated with obesity should begin as early as school grade 1, while screening for children with overweight may be more appropriate by school grade 6. These findings emphasise the need for age- and weight-specific screening strategies for children with overweight and obesity.

背景：越来越多的久坐行为和含糖饮料和超加工食品的消费增加了儿童肥胖的风险和早期发病。目的：确定健康儿童的控制衰减参数（CAP）临界值，评估超重和肥胖儿童代谢功能障碍相关脂肪变性肝病（MASLD）的患病率，并在我国人群中建立MASLD筛查的合适起始年龄。方法：招募健康小学生。使用CAP评估肝脂肪变性，并在2020年8月至2021年3月和2023年2月至2024年5月两个时期收集体成分数据。结果：1653名参与者（平均年龄9.5±1.7岁）中，976名体重正常的儿童被用于建立参考区间。肝脂肪变性定义为CAP高于247 dB/m（97.5%）。超重和肥胖儿童的MASLD患病率在一年级分别为0%和16%，在六年级分别增加到19%和75% (p结论：与肥胖相关的肝脂肪变性筛查应早在一年级开始，而超重儿童的筛查可能更适合在六年级进行。这些发现强调了对超重和肥胖儿童进行年龄和体重特异性筛查策略的必要性。

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引用次数: 0

Acute Exercise-Induced Energy Expenditure and Substrate Oxidation Rates Might Not Be Associated With Subsequent Appetitive Responses in Adolescents Living With Obesity 急性运动诱导的能量消耗和底物氧化率可能与肥胖青少年随后的食欲反应无关

IF 2.7 3区医学 Q1 PEDIATRICS

Pediatric Obesity

Pub Date : 2025-12-11 DOI: 10.1111/ijpo.70073

David Thivel, Duane Beraud, Julie Siroux, Halim Moore, Camille Marcantei, Baptiste Tarrit, Graham Finlayson, Marie-Eve Mathieu, Masashi Miyashita, Valérie Julian, Martine Duclos, Yves Boirie, Bruno Pereira, Laurie Isacco

Background

While acute exercise has been shown to alter subsequent energy intake in adolescents with obesity, the role of the exercise-induced energy expenditure and substrate oxidation remains unknown. The present study investigates the effect of energy expenditure and substrate oxidation rates during an acute walking exercise on subsequent appetitive responses in adolescents with obesity.

Methods

Body composition and maximal aerobic capacities were assessed in 25 adolescents [8 males, 12–16 years] with obesity. They then realized a control condition without exercise [CON] and an exercise session [EX, 40-min walking at 4 km h⁻¹] in a randomized order. Energy expenditure and substrate use were assessed at rest and during exercise using indirect calorimetry. Subsequent ad libitum energy intake, appetite sensations and food reward were assessed.

Results

Post-exercise energy intake was reduced on EX compared with CON [1083 ± 253 vs. 950 ± 226 kcal; p = 0.041], with reduced absolute protein intake [p = 0.011]. None of the appetite sensations differed between conditions. Pre-lunch explicit liking for fat decreased on EX compared with CON [p = 0.045], the implicit and explicit wanting for fat [p = 0.047 and p = 0.025 respectively] and explicit wanting for taste [p = 0.012] decreased from pre to post lunch after exercise. Energy Expenditure, fat and carbohydrate oxidation rates during exercise were not associated with subsequent appetitive measurements.

Conclusion

Exercise-induced energy expenditure and substrate might not be associated with the short-term control of appetite and energy intake in adolescents with obesity, which remains to be confirmed by further studies evaluating the effect of various exercises inducing specific predominant fuel sources.

虽然急性运动已被证明可以改变肥胖青少年随后的能量摄入，但运动诱导的能量消耗和底物氧化的作用尚不清楚。本研究探讨了急性步行运动中能量消耗和底物氧化率对肥胖青少年随后食欲反应的影响。方法对25例肥胖青少年[男性8例，12-16岁]进行体成分和最大有氧能力测定。然后，他们按随机顺序实现了不运动的对照条件[CON]和运动阶段[EX， 40分钟，每小时4公里]。在休息和运动时使用间接量热法评估能量消耗和底物使用。随后的随意能量摄入、食欲感觉和食物奖励被评估。结果与对照组相比，EX组运动后能量摄入减少[1083±253 vs 950±226 kcal；P = 0.041]，绝对蛋白质摄入量减少[P = 0.011]。在不同的条件下，食欲感觉都没有差异。与对照组相比，运动后的午餐前外显对脂肪的喜爱有所下降[p = 0.045]，内隐和外显对脂肪的渴望[p = 0.047和p = 0.025]和外显对味道的渴望[p = 0.012]在运动后的午餐前和午餐后有所下降。运动期间的能量消耗、脂肪和碳水化合物氧化率与随后的食欲测量结果无关。结论运动诱导的能量消耗和底物可能与肥胖青少年食欲和能量摄入的短期控制无关，这有待于进一步研究评估各种运动诱导特定优势能量源的效果。

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