Metal-catalyzed reactions for the C(sp2)–N bond formation: achievements of recent years

Abstract

The review deals with the main catalytic methods for the C(sp2)–N bond formation, including Buchwald–Hartwig palladium-catalyzed amination of aryl and heteroaryl halides, renaissance of the Ullmann chemistry, i.e., the application of catalysis by copper complexes to form the carbon–nitrogen bond, and Chan–Lam reactions of (hetero)arylboronic acids with amines. Also, oxidative amination with C–H activation, which has been booming during the last decade, is addressed. Particular attention is paid to achievements in the application of heterogenized catalysts. The bibliography includes 350 references.