Miriam B. Garcia DO, Keri L. Schadler PhD, Joya Chandra PhD, Steven K. Clinton MD, PhD, Kerry S. Courneya PhD, Zobeida Cruz-Monserrate PhD, Carrie R. Daniel PhD, MPH, Andrew J. Dannenberg MD, Wendy Demark-Wahnefried PhD, RD, Mark W. Dewhirst DVM, PhD, Carol J. Fabian MD, Stephen D. Hursting PhD, Melinda L. Irwin PhD, MPH, Neil M. Iyengar MD, Jennifer L. McQuade MD, Kathryn H. Schmitz PhD, MPH, Karen Basen-Engquist PhD, MPH
{"title":"Translating energy balance research from the bench to the clinic to the community: Parallel animal-human studies in cancer","authors":"Miriam B. Garcia DO, Keri L. Schadler PhD, Joya Chandra PhD, Steven K. Clinton MD, PhD, Kerry S. Courneya PhD, Zobeida Cruz-Monserrate PhD, Carrie R. Daniel PhD, MPH, Andrew J. Dannenberg MD, Wendy Demark-Wahnefried PhD, RD, Mark W. Dewhirst DVM, PhD, Carol J. Fabian MD, Stephen D. Hursting PhD, Melinda L. Irwin PhD, MPH, Neil M. Iyengar MD, Jennifer L. McQuade MD, Kathryn H. Schmitz PhD, MPH, Karen Basen-Engquist PhD, MPH","doi":"10.3322/caac.21773","DOIUrl":null,"url":null,"abstract":"<p>Advances in energy balance and cancer research to date have largely occurred in siloed work in rodents or patients. However, substantial benefit can be derived from parallel studies in which animal models inform the design of clinical and population studies or in which clinical observations become the basis for animal studies. The conference <i>Translating Energy Balance from Bench to Communities: Application of Parallel Animal-Human Studies in Cancer,</i> held in July 2021, convened investigators from basic, translational/clinical, and population science research to share knowledge, examples of successful parallel studies, and strong research to move the field of energy balance and cancer toward practice changes. This review summarizes key topics discussed to advance research on the role of energy balance, including physical activity, body composition, and dietary intake, on cancer development, cancer outcomes, and healthy survivorship.</p>","PeriodicalId":137,"journal":{"name":"CA: A Cancer Journal for Clinicians","volume":"73 4","pages":"425-442"},"PeriodicalIF":503.1000,"publicationDate":"2023-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.3322/caac.21773","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"CA: A Cancer Journal for Clinicians","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.3322/caac.21773","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 3
Abstract
Advances in energy balance and cancer research to date have largely occurred in siloed work in rodents or patients. However, substantial benefit can be derived from parallel studies in which animal models inform the design of clinical and population studies or in which clinical observations become the basis for animal studies. The conference Translating Energy Balance from Bench to Communities: Application of Parallel Animal-Human Studies in Cancer, held in July 2021, convened investigators from basic, translational/clinical, and population science research to share knowledge, examples of successful parallel studies, and strong research to move the field of energy balance and cancer toward practice changes. This review summarizes key topics discussed to advance research on the role of energy balance, including physical activity, body composition, and dietary intake, on cancer development, cancer outcomes, and healthy survivorship.
期刊介绍:
CA: A Cancer Journal for Clinicians" has been published by the American Cancer Society since 1950, making it one of the oldest peer-reviewed journals in oncology. It maintains the highest impact factor among all ISI-ranked journals. The journal effectively reaches a broad and diverse audience of health professionals, offering a unique platform to disseminate information on cancer prevention, early detection, various treatment modalities, palliative care, advocacy matters, quality-of-life topics, and more. As the premier journal of the American Cancer Society, it publishes mission-driven content that significantly influences patient care.