A MONOCLONAL IgM WITH SPECIFIC ANTIBODY REACTIVITY AGAINST KLEBSIELLA SERO‐TYPES 12 AND 13

J. Eriksen, M. Harboe, Johanna Deverili
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引用次数: 2

Abstract

Monoclonal IgM from the human macroglobulinaemia serum Ra showed antibody activity against type specific polysaccharide from Klebsiella type 12 and type 13. The same IgM-molecule precipitated both polysaccharides. Cross-reaction between these two Klebsiella types has not been reported previously. It could also be demonstrated with rabbit hyperimmune sera by the passive haemagglutination reaction, but not by gel precipitation or capsular swelling.
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一种对克雷伯氏菌血清型12和13具有特异性抗体反应性的单克隆IgM
从人大球蛋白血症血清Ra中提取的单克隆IgM对克雷伯氏菌12型和13型特异性多糖具有抗体活性。同样的igm分子沉淀了两种多糖。这两种克雷伯菌之间的交叉反应以前未见报道。兔高免疫血清也可以通过被动血凝反应来证明这一点,但不能通过凝胶沉淀或荚膜肿胀来证明。
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CAPSULAR SWELLING AND PASSIVE HAEMAGGLUTINATION INDUCED BY MONOCLONAL IgM REACTING WITH ACID POLYSACCHARIDES OF KLEBSIELLA A MONOCLONAL IgM WITH SPECIFIC ANTIBODY REACTIVITY AGAINST KLEBSIELLA SERO‐TYPES 12 AND 13 OCCURRENCE OF HEPATITIS B SURFACE ANTIGEN (HBs Ag) IN BLOOD DONORS AND PATIENTS SUFFERING FROM TRANSFUSION HEPATITIS PHAGOCYTOSIS AND MICROBICIDAL CAPACITY OF MOUSE MACROPHAGES NON-SPECIFICALLY ACTIVATED IN VITRO Serotype determinant protein of Neisseria Meningitidis. Large scale preparation by direct detergent treatment of the bacterial cells.
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