Synthesis and evaluation of 5-substituted-2'-deoxyuridine monophosphate analogues as inhibitors of flavin-dependent thymidylate synthase in Mycobacterium tuberculosis
Martin Kögler, Bart Vanderhoydonck, S. D. Jonghe, Jean Herman, T. Louat, K. V. Belle, J. Rozenski, P. Herdewijn
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引用次数: 12
Abstract
Synthesis and Evaluation of 5-Substituted 20-deoxyuridine Monophosphate Analogues As Inhibitors of Flavin-Dependent Thymidylate Synthase in Mycobacterium tuberculosis Martin K€ogler, Bart Vanderhoydonck, Steven De Jonghe, Jef Rozenski, Kristien Van Belle, Jean Herman, Thierry Louat, Anastasia Parchina, Carol Sibley, Eveline Lescrinier, and Piet Herdewijn* Katholieke Universiteit Leuven, Rega Institute for Medical Research, Laboratory of Medicinal Chemistry, Minderbroedersstraat 10, 3000 Leuven, Belgium Katholieke Universiteit Leuven, Interface Valorisation Platform (IVAP), Kapucijnenvoer 33, 3000 Leuven, Belgium Department of Genome Sciences, University of Washington, Seattle, Washington, United States
Martin K€ogler, Bart Vanderhoydonck, Steven De Jonghe, Jef Rozenski, Kristien Van Belle, Jean Herman, Thierry Louat, Anastasia Parchina, Carol Sibley, Eveline Lescrinier，和Piet Herdewijn*天主教鲁芬大学，Rega医学研究所，药物化学实验室，minderbroederstraat 103000 Leuven，比利时天主教鲁汶大学，界面评估平台(IVAP)， Kapucijnenvoer 33,3000 Leuven，比利时，华盛顿大学基因组科学系，西雅图，华盛顿，美国
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