Neurology

PhD Claire André, PhD Elizabeth Kuhn, PhD Stéphane Rehel, PhD Valentin Ourry, Solène Demeilliez-Servouin MSc, MSc Cassandre Palix, MSc Francesca Felisatti, MSc Pierre Champetier, MD Sophie Dautricourt, PhD Paul Yushkevich, Denis, V. De, MD La Sayette, PhD Gaël Chételat, PhD Robin de Flores, G. Rauchs, MD Andrea Schneider
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Abstract

Background and objectives: Sleep-disordered breathing (SDB) has been related to amyloid deposition and increased dementia risk. However, how SDB relates to medial temporal lobe neurodegeneration and subsequent episodic memory impairment is unclear. Our objective was to investigate the impact of amyloid positivity on the associations between SDB severity, medial temporal lobe subregions and episodic memory performance in cognitively unimpaired older adults.
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神经学
背景与目的:睡眠呼吸障碍(SDB)与淀粉样蛋白沉积和痴呆风险增加有关。然而,SDB与内侧颞叶神经变性和随后的情景记忆障碍的关系尚不清楚。我们的目的是研究淀粉样蛋白阳性对认知未受损老年人SDB严重程度、内侧颞叶亚区和情景记忆表现之间的关联的影响。
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