3D CELL BIOPRINTING FOR REGENERATIVE MEDICINE RESEARCH AND THERAPIES

C. Khatiwala, R. Law, B. Shepherd, S. Dorfman, M. Csete
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引用次数: 62

Abstract

Tissue engineering tools and technologies are critical for regenerative medicine and the translational research supporting development of cell-based therapies. 3D cell bioprinting is a relatively new engineering tool being used to design 3D cell constructs (rather than cell suspensions) for transplantation therapies. In this review, we describe a broad range of printing technologies now being used to deliver cells and biomaterials in preclinical studies. We focus on 3D cell bioprinting, in which the building blocks (or 'bioink') used in printing process are three-dimensional cell structures, that are placed by the bioprinter into precise architectures to generate small tissues or organs. 3D cell bioprinting is a flexible research tool for basic and translational stem cell biology.
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用于再生医学研究和治疗的3d细胞生物打印
组织工程工具和技术对于再生医学和支持细胞疗法发展的转化研究至关重要。3D细胞生物打印是一种相对较新的工程工具,用于设计用于移植治疗的3D细胞结构(而不是细胞悬液)。在这篇综述中,我们描述了目前在临床前研究中用于传递细胞和生物材料的广泛的打印技术。我们专注于3D细胞生物打印,其中打印过程中使用的构建块(或“生物墨水”)是三维细胞结构,由生物打印机放置到精确的结构中以生成小组织或器官。3D细胞生物打印是基础和转化干细胞生物学的一种灵活的研究工具。
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NUCLEAR REPROGRAMMING AND THE CURRENT CHALLENGES IN ADVANCING PERSONALIZED PLURIPOTENT STEM CELL-BASED THERAPIES S/MAR VECTORS — ALTERNATIVE EXPRESSION SYSTEMS FOR GENE THERAPY? MURINE PGK PROMOTER IN A LENTIVIRAL VECTOR IN CANINE LEUKOCYTE ADHESION DEFICIENCY AND IN HUMAN LAD-1 CD34+ CELLS IN NSG MICE 3D CELL BIOPRINTING FOR REGENERATIVE MEDICINE RESEARCH AND THERAPIES EDITORIAL — NOBEL PRIZE HIGHLIGHT: SOMATIC CELL REPROGRAMMING AND THE CURRENT CLINICAL GRADE CHALLENGE
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