Simulation of Dynamic Rigidity Modulus of Brain Matter by that of Agar Gel

M. Chakroun, M. H. B. Ghozlen
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Abstract

Agar gel is a linear viscoelastic material with low deformations ( < 0.01%). Here, characterization technique used is the rheometer-type Carri-Med “CSL 100”. This rheometer offers us the opportunity to study the gel in static and dynamic shear. The study is done at low frequencies (0.1–40Hz). Mechanical characterization of the agar gel in terms of dynamic modulus is performed for different concentrations. The dynamic rigidity of the gel decreases with increasing concentration. The 8% agar gel simulates very well the dynamic rigidity of brain tissue at low frequency. The range of low frequencies is rarely studied for this material (brain) in the literature. Most tests done on brain tissue are in a frequency range between 50Hz and 600Hz. Yet, the Maxwell–Kelvin–Voigt model simulates very well the 8% agar gel. The instant elasticity derived from mathematical modeling of agar gel is similar to that measured in the literature for the brain tissue. Hence agar gel can be used in the construction of physical models of the human head used to analyze the dynamic response of the head to shock or to an inertial load.
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琼脂凝胶模拟脑物质动态刚度模量
琼脂凝胶是一种低变形(< 0.01%)的线性粘弹性材料。在这里,使用的表征技术是流变仪型carrier - med“CSL 100”。该流变仪使我们有机会研究凝胶的静态和动态剪切。该研究在低频率(0.1-40Hz)下进行。琼脂凝胶的力学特性在动态模量方面进行了不同的浓度。凝胶的动刚度随浓度的增加而降低。8%琼脂凝胶能很好地模拟低频下脑组织的动态刚度。文献中很少对这种物质(大脑)的低频范围进行研究。对脑组织进行的大多数测试的频率范围在50Hz到600Hz之间。然而,麦克斯韦-开尔文-沃伊特模型很好地模拟了8%琼脂凝胶。从琼脂凝胶的数学模型中得到的瞬时弹性与文献中测量的脑组织相似。因此,琼脂凝胶可用于构建人体头部的物理模型,用于分析头部对冲击或惯性载荷的动态响应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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