Trabecular Bone Changes in Ovariectomized Rabbit Mandibles

T. Cao, T. Shirota, Y. Kamon, K. Ohno
{"title":"Trabecular Bone Changes in Ovariectomized Rabbit Mandibles","authors":"T. Cao, T. Shirota, Y. Kamon, K. Ohno","doi":"10.11516/DENTALMEDRES1981.24.11","DOIUrl":null,"url":null,"abstract":"Numerous clinical studies have suggested that the greater risk for oral bone loss in females may be correlated with osteoporosis after menopause. Knowledge of trabecular changes in edentulous bedding bone in animals with loss of ovarian function may be beneficial in the planning and treating of dental implants in postmenopausal women. The purpose of this study was to evaluate trabeculae changes in edentulous bedding bone for dental implantation in ovariectomized rabbits. Twelve adult female Japanese white rabbits were examined. The mandibular incisors were initially extracted to simulate the edentulous bedding bone for dental implants. Six animals were bilaterally ovariectomized and the other 6 were sham-ovariectomized 12 weeks after tooth extraction. The edentulous parts of distal mandibular bodies were processed undecalcified 12 weeks after ovariectomy or sham-ovariectomy and examined by quantitative trabecular bone histomorphometry. In ovariectomized rabbits, there were significant increases in trabecular separation, osteoid volume, osteoid thickness, osteoid width, eroded surface, and mineral appositional rate, and a significant decrease in trabeculae number. The results of sparser trabecular structure, more trabecular osteoid, and increased trabecular bone turnover demonstrate bone loss of mandibular edentulous trabeculae in ovariectomized rabbits and suggest that the same loss may occur in postmenopausal women.","PeriodicalId":77624,"journal":{"name":"Showa Shigakkai zasshi = The Journal of Showa University Dental Society","volume":"24 1","pages":"11-17"},"PeriodicalIF":0.0000,"publicationDate":"2004-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Showa Shigakkai zasshi = The Journal of Showa University Dental Society","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.11516/DENTALMEDRES1981.24.11","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Numerous clinical studies have suggested that the greater risk for oral bone loss in females may be correlated with osteoporosis after menopause. Knowledge of trabecular changes in edentulous bedding bone in animals with loss of ovarian function may be beneficial in the planning and treating of dental implants in postmenopausal women. The purpose of this study was to evaluate trabeculae changes in edentulous bedding bone for dental implantation in ovariectomized rabbits. Twelve adult female Japanese white rabbits were examined. The mandibular incisors were initially extracted to simulate the edentulous bedding bone for dental implants. Six animals were bilaterally ovariectomized and the other 6 were sham-ovariectomized 12 weeks after tooth extraction. The edentulous parts of distal mandibular bodies were processed undecalcified 12 weeks after ovariectomy or sham-ovariectomy and examined by quantitative trabecular bone histomorphometry. In ovariectomized rabbits, there were significant increases in trabecular separation, osteoid volume, osteoid thickness, osteoid width, eroded surface, and mineral appositional rate, and a significant decrease in trabeculae number. The results of sparser trabecular structure, more trabecular osteoid, and increased trabecular bone turnover demonstrate bone loss of mandibular edentulous trabeculae in ovariectomized rabbits and suggest that the same loss may occur in postmenopausal women.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
兔下颌骨去卵巢后骨小梁的变化
大量临床研究表明,绝经后女性口腔骨质流失风险增大可能与骨质疏松症有关。了解卵巢功能丧失动物无牙床骨的骨小梁变化可能有助于绝经后妇女种植牙的计划和治疗。本研究的目的是评价无牙铺垫骨在兔去卵巢植牙时的骨小梁变化。对12只成年雌性日本大白兔进行了检查。初步拔除下颚门牙,模拟无牙植牙的垫层骨。6只在拔牙12周后进行双侧卵巢切除,6只进行假卵巢切除。在卵巢切除或假卵巢切除12周后,对下颌远端体无牙部分进行未钙化处理,并进行定量骨小梁组织形态学测定。卵巢切除兔骨小梁分离、骨样体积、骨样厚度、骨样宽度、侵蚀面、矿物附着率显著增加,骨小梁数量显著减少。小梁结构稀疏、小梁类骨增多和小梁骨转换增加的结果表明,切除卵巢的家兔下颌无牙小梁骨丢失,并提示绝经后妇女也可能发生同样的丢失。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
術前顎矯正治療(NAM)が哺乳へ与える影響について 裂型別にみる哺乳障害の現状アンケート調査 SEM and TEM Observation of Ultra Microstructure at Adhesive Interface between Resin and Caries Affected Dentin Suppression of Visceromotor Function Induced by Noxious Stimulation to the Oral-facial Region in the Rat Noggin Prevents Osteogenesis but Induces Chondrogenesis in a Human Mesenchymal Cell Line (USAC) Electromyographic Evaluation of Masticatory Muscles Following Surgical Orthodontics with Skeletal Mandibular Prognathism
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1