Biochemical Predictors of New-Onset Atrial Fibrillation after Ascending Aorta Replacement Surgery in Acute Type A Aortic Dissection Patients

IF 1.3 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Journal of Cardiac Surgery Pub Date : 2023-02-08 DOI:10.1155/2023/2612292
Jian Shi, Yong Cheng, Xiyu Zhu, Ze-Yi Zhou, Yi Jiang, Y. Xue, H. Cao, Dong-jin Wang
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Abstract

Objective. This study aimed to determine the risk factors of new-onset postoperative atrial fibrillation after ascending aortic replacement in acute type A aortic dissection patients, with emphasis on biochemical parameters. Methods. From Jan 2020 to Dec 2021, a total of 435 acute type A aortic dissection patients who underwent ascending aortic replacement and without a history of atrial fibrillation were retrospectively analyzed in this study. Perioperative data of these patients were obtained from the hospital’s database. The 30-day follow-up was via telephone interviews. The multivariate regression analysis was used to identify risk factors that may be predictive of postoperative atrial fibrillation. Results. 218 (50.1%) patients experienced postoperative atrial fibrillation after ascending aorta replacement surgery. Older age (OR = 1.081 (1.059–1.104), p < 0.001 ), higher total bile acid (OR = 1.064 (1.024–1.106), p  = 0.002), glucose (OR = 1.180 (1.038–1.342), p  = 0.012), and serum potassium (OR = 2.313 (1.078–4.960), p  = 0.031) were identified by multivariate regression analysis as risk factors of postoperative atrial fibrillation. The multivariate regression analysis prediction model incorporating these four factors had a good prediction effect (AUC = 0.769 (0.723–0.816), p < 0.001 ). Conclusions. Older age, higher total bile acid, glucose, and serum potassium were risk factors of postoperative atrial fibrillation after ascending aortic replacement surgery in acute type A aortic dissection patients.
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急性A型主动脉夹层患者升主动脉置换术后新发房颤的生化预测指标
目标。本研究旨在确定急性A型主动脉夹层患者升主动脉置换术后新发房颤的危险因素,重点关注生化指标。方法。本研究回顾性分析了2020年1月至2021年12月期间行升主动脉置换术且无房颤史的435例急性a型主动脉夹层患者。这些患者的围手术期数据来自医院的数据库。30天的随访是通过电话采访进行的。多因素回归分析用于确定可能预测术后房颤的危险因素。结果:218例(50.1%)患者在升主动脉置换术后发生房颤。多因素回归分析发现,年龄较大(OR = 1.081 (1.059 ~ 1.104), p < 0.001)、总胆汁酸升高(OR = 1.064 (1.024 ~ 1.106), p = 0.002)、血糖升高(OR = 1.180 (1.038 ~ 1.342), p = 0.012)、血钾升高(OR = 2.313 (1.078 ~ 4.960), p = 0.031)是术后房颤的危险因素。纳入这4个因素的多元回归分析预测模型预测效果较好(AUC = 0.769 (0.723-0.816), p < 0.001)。结论。高龄、总胆酸、血糖、血钾升高是急性A型主动脉夹层患者升主动脉置换术后房颤发生的危险因素。
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来源期刊
CiteScore
2.90
自引率
12.50%
发文量
976
审稿时长
3-8 weeks
期刊介绍: Journal of Cardiac Surgery (JCS) is a peer-reviewed journal devoted to contemporary surgical treatment of cardiac disease. Renown for its detailed "how to" methods, JCS''s well-illustrated, concise technical articles, critical reviews and commentaries are highly valued by dedicated readers worldwide. With Editor-in-Chief Harold Lazar, MD and an internationally prominent editorial board, JCS continues its 20-year history as an important professional resource. Editorial coverage includes biologic support, mechanical cardiac assist and/or replacement and surgical techniques, and features current material on topics such as OPCAB surgery, stented and stentless valves, endovascular stent placement, atrial fibrillation, transplantation, percutaneous valve repair/replacement, left ventricular restoration surgery, immunobiology, and bridges to transplant and recovery. In addition, special sections (Images in Cardiac Surgery, Cardiac Regeneration) and historical reviews stimulate reader interest. The journal also routinely publishes proceedings of important international symposia in a timely manner.
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