Lumbosacral prolotherapy

A. Jacks, T. Barling
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Abstract

In Yelland’s comments on our paper in Int Musculoskelet Med 2012; 34:7–12, he makes a number of excellent points with which we generally agree; however, we wish to clarify some points and to build on others. We accept the uncertainty of the exact definition of instability but this should not prevent us from agreeing a reasonably uniform client base on whom to try to refine the efficacy of a treatment that seems to work well. Our subjects with lumbar or pelvic pain who had a diminishing response to manipulation were just one subgroup of several described, indeed some had no discernible dysfunction to manipulate. Our patients were all treated on three occasions rather than up to seven times as in Yelland’s cases and whereas he treated only tender entheses, we treat bilateral ligament attachments across affected segments even if there is only unilateral tenderness. We feel as does Yelland that both studies compare favourably with spinal fusion and that our group was also ‘from the difficult end of the spectrum’ – constituting only 5 and 9%, respectively, of our clinics’ patients. With regard to future research we support Yelland’s proposal that an extended series analysed carefully for subgroups is a practical way forward. Both of us have continued to collect the same data since publication and will be able to analyse subgroups further by factors such as ligament group treated (e.g. sacroiliac, iliolumbar, or lumbosacral) sex, age, and length of initial history. Further subgroups would require a considerable amount of work. We favour this approach since we already have the data collection process in place but as Yelland states so clearly in conclusion there is plenty of room for more research in this area.
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腰骶的增生疗法
在Yelland对我们发表在2012年《Int musculoskeletal Med》上的论文的评论中;34:7-12,他提出了一些我们普遍同意的优秀观点;然而,我们希望澄清一些问题,并在其他问题的基础上加以补充。我们接受不稳定性确切定义的不确定性,但这不应妨碍我们就合理统一的客户基础达成一致意见,以尝试改进一种似乎效果良好的治疗方法的疗效。我们研究的腰椎或骨盆疼痛患者对操作的反应减弱,这只是所描述的几个亚组中的一个,实际上有些患者没有明显的操作功能障碍。我们的患者都接受了三次治疗,而不是像Yelland的病例那样多达七次,而他只治疗有压痛的囊肿,我们治疗受影响节段的双侧韧带附着,即使只有单侧压痛。我们和Yelland一样认为,这两项研究与脊柱融合术相比都是有利的,而且我们的小组也“来自困难的一端”——分别只占我们诊所病人的5%和9%。关于未来的研究,我们支持Yelland的建议,即对子群体进行仔细分析的扩展系列是一种实际的前进方式。自发表以来,我们两人都继续收集相同的数据,并将能够根据治疗的韧带组(如骶髂、髂腰椎或腰骶)、性别、年龄和初始病史长度等因素进一步分析亚组。进一步的子组将需要大量的工作。我们赞成这种方法,因为我们已经有了数据收集过程,但正如Yelland在结论中明确指出的那样,在这一领域还有大量的研究空间。
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