{"title":"Mechanism and Function of Angiogenin in Apoptosis Regulation.","authors":"L. Shu-ping, H. Guo-fu","doi":"10.13865/J.CNKI.CJBMB.2015.12.05","DOIUrl":null,"url":null,"abstract":"Angiogenin (ANG), a secreted ribonuclease, has been characterized recently as an anti-apoptosis factor involved in a variety of cellular anti-apoptosis process. ANG regulates intrinsic pathways-related major molecules such as anti-apoptotic protein Bcl-2, as well as extrinsic signaling pathways. Moreover, ANG regulates p53-regulated apoptosis, a process considered to be important in regulating both the extrinsic and the intrinsic pathways.","PeriodicalId":9907,"journal":{"name":"中国生物化学与分子生物学报","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中国生物化学与分子生物学报","FirstCategoryId":"1089","ListUrlMain":"https://doi.org/10.13865/J.CNKI.CJBMB.2015.12.05","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 6
Abstract
Angiogenin (ANG), a secreted ribonuclease, has been characterized recently as an anti-apoptosis factor involved in a variety of cellular anti-apoptosis process. ANG regulates intrinsic pathways-related major molecules such as anti-apoptotic protein Bcl-2, as well as extrinsic signaling pathways. Moreover, ANG regulates p53-regulated apoptosis, a process considered to be important in regulating both the extrinsic and the intrinsic pathways.
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