T. Ikegami, Masatoshi Yamamoto, Yoshihiro Sato, Masaharu Takahashi, S. Usuda, M. Maeda, A. Tsuji
{"title":"Development of a Fully Automated Chemiluminescent Enzyme Immunoassay for GOR Antibody","authors":"T. Ikegami, Masatoshi Yamamoto, Yoshihiro Sato, Masaharu Takahashi, S. Usuda, M. Maeda, A. Tsuji","doi":"10.14921/JSCC1971B.23.4_299","DOIUrl":null,"url":null,"abstract":"We developed an anti-GOR assay using the LuminomasterTM system, a fully automated, random access chemiluminescent enzyme immunoassay system. GOR antibody, which is often detected in the serum of patients infected withHepatitis C virus (HCV), is closely associated with HCV infection. This new assay provides detection of GOR antibody in 45 min, about half the time of existing EIA methods. The standard curve is 0.1-300 GOR unit/ml (1/10th-300 times cut-off value), giving a detection range about 30 times greater than that of existing assays. This greater detection","PeriodicalId":39360,"journal":{"name":"Japanese Journal of Clinical Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1994-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Japanese Journal of Clinical Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14921/JSCC1971B.23.4_299","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Biochemistry, Genetics and Molecular Biology","Score":null,"Total":0}
引用次数: 0
Abstract
We developed an anti-GOR assay using the LuminomasterTM system, a fully automated, random access chemiluminescent enzyme immunoassay system. GOR antibody, which is often detected in the serum of patients infected withHepatitis C virus (HCV), is closely associated with HCV infection. This new assay provides detection of GOR antibody in 45 min, about half the time of existing EIA methods. The standard curve is 0.1-300 GOR unit/ml (1/10th-300 times cut-off value), giving a detection range about 30 times greater than that of existing assays. This greater detection