Potential Antihyperlipidemic Effect of Edaravone against Triton X-100 and High Fat Diet (HFD) Induced Experimental Model of Hyperlipidemia in Rats

Soni D, Choudhary R, Samal Pk
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Abstract

Background: Hyperlipidemia is a condition in which blood lipid levels are greater than the normal range, and it is a major risk factor for the development of cardiac heart diseases. It affects 25-30% of the urban and 15-20% of the rural population. The current hyperlipidemia classification schemes and treatment levels are based on the Adult Treatment Program-3 guidelines issued by the National Cholesterol Education Panel, but there is no permanent treatment. So, the present study was aimed to investigate the antihyperlipidemic effect of Edaravone in Triton-X 100 and High Fat Diet-induced hyperlipidemic rat models.
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依达拉奉对Triton X-100和高脂饮食(HFD)诱导的大鼠高脂血症实验模型的潜在降脂作用
背景:高脂血症是一种血脂水平高于正常范围的疾病,是心脏疾病发展的主要危险因素。它影响着25-30%的城市人口和15-20%的农村人口。目前的高脂血症分类方案和治疗水平是基于国家胆固醇教育小组发布的成人治疗方案-3指南,但没有永久性的治疗方法。因此,本研究旨在探讨依达拉奉在triton - x100和高脂饮食诱导的高脂血症大鼠模型中的降血脂作用。
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