Kronik psikiyatri hastalarında inflamasyon: nötrofil/lenfosit, platelet/lenfosit oranları ve ortalama trombosit hacmi

Abstract

Objective: The aim of this study was to examine the Neutrophil/Lymphocyte Ratio(NLR), Platelet/Lymphocyte Ratios(PLR), and Mean Platelet Volume(MPV), red blood cell distribution width(RDW) and leukocyte cell levels of patients with Axis-I psychiatric disease by comparing them with each other and healthy controls. Material and Methods: A total of 600 people were included in our study, 500 of whom were taken as the patient and 100 as the control group. The diagnosis of patients according to DSM-5-Criteria were 34.8% Schizophrenia, 21% had Generalized-Anxiety-Disorder, 14.4% had Bipolar-Affective-Disorder, 14% had Major-Depressive-Disorder, 7.2% had Adjustment-Disorder, 4.2% had Schizoaffective-Disorder, 3.6% had other psychiatric illnesses. Results: It was seen that hemoglobin, platelet, monocyte, blood platelet distribution (PCT), percentage account of RDW (RDW-CV) did not have statistically significant differences between groups (p values were 0.082, 0.214, 0.526, 0.082, 0.771, respectively). The lymphocyte, eosinophil, basophil, MPV, standard deviation of RDW (RDW-SD) were higher compared with healthy controls (p values were 0.002, 0.003,