Leishmaniasis of the ear treated successfully by photodynamic therapy

H. Bay, S. Elloudi, S. Benkirane, Z. Douhi, S. Gallouj, F. Mernissi
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Abstract

Cutaneous Leishmaniasis (CL) are zoonoses caused by parasites of the genus Leishmania, transmission occurs by bite of a gnat called sandfly. It is a worldwide health problem. In fact, The World Health Organization (WHO) considers leishmaniasis to be one of the most serious parasitic diseases including Morocco because of the global warming [1,2]. In Morocco, major leshmaniasis, tropica and infantum are prevalent and are very common [2]. Among the problems reported in the treatment of cutaneous leishmaniosis are difficulty in determining clinical diagnosis due to lack of access tomicroscopy onmany basic health services [3]; the serious side effects of pentavalent antimonial drugs and the variability of the efficacy against the different forms of Leishmania [3], making drugs and medical attention an expensive treatment because of the side effects [3]; besides, there have also been reports of patients not responding to drugs due to drug resistance or increased immunosuppression [3]. Photodynamic Therapy (PDT) is non-invasive therapy and can be repeated when necessary without damage to the patient’s health and without causing resistance in the parasite [4-7]. We report a case illustrate this difficulty to diagnosis and treat leshmaniasis in the immunocompromised who was treated successfully by (PDT).
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光动力疗法成功治疗耳利什曼病
皮肤利什曼病是由利什曼属寄生虫引起的人畜共患疾病,通过白蛉叮咬传播。这是一个世界性的健康问题。事实上,由于全球变暖,世界卫生组织(WHO)认为利什曼病是包括摩洛哥在内的最严重的寄生虫病之一[1,2]。在摩洛哥,主要的利什曼病、热带病和婴儿病很流行,而且很常见。皮肤利什曼病治疗中报告的问题包括:由于许多基本卫生服务机构缺乏显微镜检查,难以确定临床诊断[b];五价锑药物的严重副作用以及对不同形式利什曼原虫[3]的疗效差异,由于副作用[3],使药物和医疗护理成为昂贵的治疗;此外,也有患者因耐药或免疫抑制bbb增加而对药物无反应的报道。光动力疗法(PDT)是一种非侵入性疗法,可以在必要时重复进行,不会损害患者的健康,也不会引起寄生虫的耐药性[4-7]。我们报告了一个病例,说明这种困难的诊断和治疗利什曼病在免疫功能低下谁是成功的治疗(PDT)。
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