Laser-intraocular lenses interaction: Aspects to consider for in situ vision correction

G. Kareliotis, E. Drakaki, C. Bacharis, M. Makropoulou, A. Serafetinides
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Abstract

Today, 60 years after the laser discovery, the long experience in refractive surgery, the evaluation of the accumulated clinical outcomes and the limitations of kerato- refractive surgery generated the demand to develop alternative methods for treating vision defects. In the frame of this new philosophy for vision correction, the use of polymeric intraocular lenses (IOLs) provides sufficient predictability and optical quality. The new Ophthalmology era takes their use one step further, through the IOLs’ customization, aiming at the long desired personalized treatment. Inspired by the need to correct some post-operative complications in cataract surgery and IOLs implantation, the laser use is proposed, for in situ refractive modification of the implanted polymeric material, without any alteration in IOL’s light transmittance behavior. In this work we present a brief literature overview of new perspectives in this field, enriched with some of our experimental studies. Through discussion of the laser-material interactions we intend to present the prospects, the limitations and the aspects that have to be considered in the route for in situ laser-based IOL- surgery and finally, vision correction.
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激光-人工晶状体相互作用:原位视力矫正需要考虑的方面
今天,在激光发现60年后,长期的屈光手术经验,对积累的临床结果的评估以及角膜屈光手术的局限性产生了开发治疗视力缺陷的替代方法的需求。在这种新的视力矫正理念的框架下,使用聚合物人工晶状体(iol)提供了足够的可预测性和光学质量。新的眼科时代通过人工晶状体的定制,使它们的使用更进一步,旨在实现长期期望的个性化治疗。由于白内障手术和人工晶状体植入术中需要纠正一些术后并发症,提出了在不改变人工晶状体透光性的情况下,利用激光对植入的聚合物材料进行原位屈光性改变。在这项工作中,我们简要概述了该领域的新观点,并丰富了我们的一些实验研究。通过对激光与材料相互作用的讨论,我们打算提出基于原位激光的人工晶状体手术和视力矫正的前景、局限性和必须考虑的方面。
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