Evaluation of skin prick test, exclusion diet and dietary challenge in the diagnosis of food allergy in dogs with chronic pruritus

IF 0.8 4区 农林科学 Q3 VETERINARY SCIENCES Pesquisa Veterinaria Brasileira Pub Date : 2023-08-07 DOI:10.1590/1678-5150-pvb-7196
C. Alcalá, J. Possebom, Lucas A. Ludwig, A.P.S. Cerdeiro, Raniere Gaertner, M. Farias
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Abstract

ABSTRACT: Allergic dogs are commonly sensitized to food allergens. We evaluated the use of the prick test to diagnose food allergies in dogs with pruritus and the efficacy of an exclusion diet based on the test. The prick test was performed in 10 healthy dogs and 34 dogs with pruritus, of which 25 received an exclusion diet for 60 days and was challenged with positive food on the test. pVAS and CADESI-4 were assessed on days 0, 30, and 60 after re-exposure. As a result, two control group dogs reacted to a single food allergen, milk and wheat. Of the 25 dogs with pruritus that reacted to food allergens, 24 (96%) reacted to more than one food allergen, and only one (4%) reacted to a single food protein: pork. In the test group (n=25), there was a significant improvement of pVAS and CADESI-4 after 30 and 60 days of dietary exclusion, with significant worsening of the scores with food allergen challenge. In conclusion, the prick test can be used for screening food allergens to make an exclusion diet.
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皮肤点刺试验、排斥饮食和饮食刺激对慢性瘙痒犬食物过敏诊断的评价
摘要:过敏犬通常对食物过敏原敏感。我们评估了针刺试验诊断瘙痒犬食物过敏的应用,以及基于该试验的排除性饮食的效果。对10只健康犬和34只瘙痒犬进行点刺试验,其中25只给予排除性饮食60 d,并给予阳性食物挑战。pVAS和CADESI-4在再次暴露后的第0、30和60天进行评估。结果,对照组的两只狗对牛奶和小麦这一单一食物过敏原产生了反应。在25只对食物过敏原有反应的瘙痒犬中,24只(96%)对一种以上的食物过敏原有反应,只有一只(4%)对一种食物蛋白质有反应:猪肉。试验组(n=25)在排除饮食30天和60天后,pVAS和CADESI-4得分均有显著改善,食物过敏原攻击后得分显著恶化。由此可见,针刺试验可用于筛选食物过敏原,制定排除性饮食。
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来源期刊
Pesquisa Veterinaria Brasileira
Pesquisa Veterinaria Brasileira 农林科学-兽医学
CiteScore
1.30
自引率
16.70%
发文量
41
审稿时长
9-18 weeks
期刊介绍: Pesquisa Veterinária Brasileira - Brazilian Journal of Veterinary Research (http://www.pvb.com.br), edited by the Brazilian College of Animal Pathology in partnership with the Brazilian Agricultural Research Organization (Embrapa) and in collaboration with other veterinary scientific associations, publishes original papers on animal diseases and related subjects. Critical review articles should be written in support of original investigation. The editors assume that papers submitted are not being considered for publication in other journals and do not contain material which has already been published. Submitted papers are peer reviewed. The abbreviated title of Pesquisa Veterinária Brasileira is Pesqui. Vet. Bras.
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