Efeito de um dentifrício fluoretado contendo bicarbonato de sódio na contagem de estreptococos do grupo mutans, acidogenicidade e composição da placa dental

Rosa Fernanda Ignácio, P. E. C. Peres, J. Cury
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引用次数: 9

Abstract

This investigation evaluated the effect of a fluoride baking soda-containing dentifrice on mutans streptococci counting, acidogenicity and composition of dental plaque. Twenty-three volunteers brushing their teeth 3 times a day, tested 3 formulations of fluoride (1500 ppm F), containing or sodium bicarbonate (12%) associated with calcium carbonate (CARB/BICAR), or calcium carbonate (CARBONATE), or silica (SILICA), in a double blind crossover trial, done in 3 phases of 30 days each. On the 28th day, 8-10 hours after the last brushing, a counting of mutans streptococci in saliva (SMS) was made. On the 30th day (after 48 hours during which the subjects were instructed to rinse with a slurry of toothpaste/water 3 times a day and sucrose 10% 6 times a day), the effect was analyzed in dental plaque, 10-12 hours after the last rinse: a) mutans streptococci (PMS); b) polysaccharide alkali-soluble (ASP); c) acid-soluble F (ASF) and d) pH in T0 (T0), 5 min. after cariogenic challenge (T5), calculating DpH (T0 - T5). The results (mean + SE) according to the treatments with dentifrices SILICA, CARBONATE and CARB/BICAR, were respectively: 1) SMS (x 106 UFC/mL saliva) = 11.43 + 7.62 A; 2,33 + 1.04 A; 2.07 + 1.10 A; 2) PMS (x 106 UFC/mg) = 0.099 + 0.095 A; 0.027 + 0.018 A; 0.007 + 0.003 A; 3) ASP (mg/mg) = 6.89 + 0.62 AC; 8.46 + 0.80 AB; 6.11 + 0.59 C; 4) ASF (mg/g) = 36.67 + 10.10 A; 48.12 + 19.23 A; 52.21 + 15.12 A; 5) T0 = 6.72 + 0.12 A; 6.88 + 0.13 A; 6.65 + 0.11 A; 6) T5 = 5.61 + 0.13 A; 5.71 + 0.13 A; 5.70 + 0.12 A; 7) DpH = 1.12 + 0.11 A; 1.17 + 0.11 A; 0.95 + 0.10 A. Means followed by the same letter do not differ significantly (P < 0.05). The data show that although the baking soda-containing dentifrice demonstrated, collectively, a trend to influence positively the various factors of dental caries, it did not differ significantly from SILICA and CARBONATE dentifrices.
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含碳酸氢钠的氟化牙膏对变形链球菌计数、致酸性和牙菌斑组成的影响
本研究评价含氟小苏打牙膏对变形链球菌计数、致酸性和牙菌斑组成的影响。在一项双盲交叉试验中,23名志愿者每天刷牙3次,测试了3种氟化物(1500 ppm F)配方,含有碳酸氢钠(12%)或碳酸钙(CARB/BICAR),或碳酸钙(碳酸盐)或二氧化硅(二氧化硅),分3个阶段进行,每个阶段30天。第28天,末次刷牙后8 ~ 10 h,进行唾液中变形链球菌计数(SMS)。在第30天(48小时后,受试者被指示用牙膏/水的浆液每天冲洗3次,蔗糖10%每天冲洗6次),在最后一次冲洗后10-12小时对牙菌斑进行影响分析:a)变形链球菌(PMS);b)多糖碱溶性(ASP);c)酸溶性F (ASF)和d) T0的pH (T0),蛀牙后5分钟(T5),计算DpH (T0 - T5)。结果(平均值+ SE)分别为:1)SMS (x 106 UFC/mL唾液)= 11.43 + 7.62 A;2,33 + 1.04 a;2.07 + 1.10 a;2) PMS (x 106 UFC/mg) = 0.099 + 0.095 A;0.027 + 0.018 a;0.007 + 0.003 a;3) ASP (mg/mg) = 6.89 + 0.62 AC;8.46 + 0.80 ab;6.11 + 0.59 c;4) ASF (mg/g) = 36.67 + 10.10 A;48.12 + 19.23 a;52.21 + 15.12 a;5) t0 = 6.72 + 0.12 a;6.88 + 0.13 a;6.65 + 0.11 a;6) t5 = 5.61 + 0.13 a;5.71 + 0.13 a;5.70 + 0.12 a;7) DpH = 1.12 + 0.11 A;1.17 + 0.11 a;0.95 + 0.10 a同字母后的平均值无显著差异(P < 0.05)。数据显示,虽然含小苏打的牙膏总体上对龋病的各个因素有积极的影响趋势,但与二氧化硅和碳酸盐牙膏的差异不显著。
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