Avaliação in situ de um dentifrício contendo MFP/DCPD na incorporação de flúor e remineralização do esmalte dental humano

Revista de odontologia da Universidade de Sao Paulo Pub Date : 1999-07-01 DOI:10.1590/S0103-06631999000300007

Hyun Koo, J. Cury

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引用次数: 5

Abstract

The aim of this study was to evaluate in situ the effectiveness of a dentifrice containing monofluorophosphate (MFP) and dicalcium phosphate dihydrate (DCPD). Eight volunteers took part in this crossover, double blind design study performed in two phases of 45 days. The subjects were acrylic resin appliances containing four blocks of human dental enamel with artificial caries to evaluate fluoride uptake and remineralization by MFP/DCPD and Placebo dentifrices. After each phase the blocks of enamel were removed and the analysis of total fluoride (ppm F) and microhardness (Knoop) were evaluated. The results of total integrated areas under the curves of the two dentifrices treatments showed that the MFP/DCPD dentifrice produced a significantly higher fluoride uptake than the Placebo dentifrice (4508.55 ± 965.82 and 1485.51 ± 191.72, respectively) and the microhardness data demonstrated 34% and -14% of remineralization for MFP/DCPD and Placebo dentifrices, respectively. It was concluded that MFP/DCPD dentifrice was effective not only on fluoride uptake, but also on remineralization of artificial caries lesions of human dental enamel.

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一种含MFP/DCPD的牙膏在人牙釉质中加入氟化物和再矿化的原位评价

本研究的目的是原位评价含有单氟磷酸盐(MFP)和二水磷酸二钙(DCPD)的牙膏的有效性。8名志愿者参加了这项交叉双盲设计研究，分两个阶段进行，为期45天。研究对象是含有4块人工龋齿的人牙釉质的丙烯酸树脂矫治器，以评估MFP/DCPD和安慰剂牙膏对氟的吸收和再矿化。每个阶段结束后，去除牙釉质块，并评估总氟化物(ppm F)和显微硬度(Knoop)。两种牙剂曲线下的总积分面积结果显示，MFP/DCPD牙剂的氟吸收量显著高于安慰剂牙剂(分别为4508.55±965.82和1485.51±191.72)，显微硬度数据显示MFP/DCPD牙剂和安慰剂牙剂的再矿化率分别为34%和-14%。结果表明，MFP/DCPD牙液不仅对氟的吸收有效，而且对人牙釉质人工龋齿的再矿化也有一定的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Revista de odontologia da Universidade de Sao Paulo

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