Sílvia Magaly Sasso Carvalho, A. Polizello, D. P. Leitão, A. Spadaro
{"title":"In vivo and in vitro studies of a cetylamine fluoride mouthrinse: evaluation of a device used for in vitro experiments","authors":"Sílvia Magaly Sasso Carvalho, A. Polizello, D. P. Leitão, A. Spadaro","doi":"10.1590/S0103-06631999000300006","DOIUrl":null,"url":null,"abstract":"A mouthrinse containing cetylamine fluoride (230 ppm in fluoride) was prepared for in vitro studies of fluoride clearance and adsorption by enamel and/or hydroxyapatite using a device that simulates the oral cavity. In vivo studies of fluoride clearance from this mouthrinse were conducted and compared with other fluoride sources. The amount of fluoride adsorbed to tooth blocks or powdered hydroxyapatite, both treated with this cetylamine fluoride mouthrinse once or twice a day, was determined. The results of these studies showed that it is possible to prepare a mouthrinse with cetylamine fluoride for alternative use by patients for the prevention and therapy of dental caries.","PeriodicalId":77611,"journal":{"name":"Revista de odontologia da Universidade de Sao Paulo","volume":"13 1","pages":"239-244"},"PeriodicalIF":0.0000,"publicationDate":"1999-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista de odontologia da Universidade de Sao Paulo","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1590/S0103-06631999000300006","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A mouthrinse containing cetylamine fluoride (230 ppm in fluoride) was prepared for in vitro studies of fluoride clearance and adsorption by enamel and/or hydroxyapatite using a device that simulates the oral cavity. In vivo studies of fluoride clearance from this mouthrinse were conducted and compared with other fluoride sources. The amount of fluoride adsorbed to tooth blocks or powdered hydroxyapatite, both treated with this cetylamine fluoride mouthrinse once or twice a day, was determined. The results of these studies showed that it is possible to prepare a mouthrinse with cetylamine fluoride for alternative use by patients for the prevention and therapy of dental caries.
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