Clinical and epidemiological characteristics of opisthorchiasis in the Republic of Mordovia

Q4 Medicine Infektsionnye Bolezni Pub Date : 2021-01-01 DOI:10.20953/1729-9225-2021-3-78-84

N.S. Markosyan, V. Pavelkina, N. P. Ampleeva, R. Z. Almyasheva, A. A. Erovichenkov

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引用次数: 1

Abstract

Objective. To analyze clinical and epidemiological characteristics of opisthorchiasis in the Republic of Mordovia. Materials and methods. We have analyzed medical records of 34 patients with opisthorchiasis (6 with acute disease and 28 with chronic disease) treated in the Republican Clinical Hospital for Infectious Diseases between 2011 and 2020. The diagnosis was confirmed by the detection of eggs of Opisthorchis felineus in their feces by microscopy. Results. The territory of Mordovia is considered endemic for opisthorchiasis. New cases are registered every year, while the incidence is lower than that in Russia. The highest incidence was observed among urban residents over 40 years of age, primarily in women. All patients reported that they ate lightly salted and dried fish (carp) not tested for its safety. Conclusion. Acute opisthorchiasis developed as the hepatocholangitic variant of the disease with fever, intoxication, pain, and jaundice. Chronic opisthorchiasis was characterized by various, but less pronounced gastrointestinal symptoms; general intoxication was less common than in patients with acute disease. Clinical manifestations of allergosis were observed only in patients with chronic infection, whereas its more pronounced laboratory signs were detected in patients with acute opisthorchiasis. Chronic infection was characterized by less significant changes in other laboratory parameters. Praziquantel was used to treat opisthorchiasis. Keywords: diagnosis, clinical manifestations, treatment, opisthorchiasis, acute, chronic, epidemiological analysis

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摩尔多瓦共和国阿片类兴奋剂病的临床和流行病学特征

目标。目的:分析莫尔多维亚共和国血吸虫病的临床和流行病学特征。材料和方法。我们分析了2011 - 2020年在共和传染病临床医院治疗的34例蛇胸蚴病患者的病历，其中急性病6例，慢性病28例。显微镜下在其粪便中检出猫腹蛇卵，证实了诊断。结果。莫尔多维亚地区被认为是蛇胸虫病的地方病。每年都有新病例登记，但发病率低于俄罗斯。发病率最高的是40岁以上的城市居民，主要是妇女。所有患者报告说，他们吃了未经安全检测的淡盐和干鱼(鲤鱼)。结论。急性蛇胸腺病发展为肝胆管病变，伴有发热、中毒、疼痛和黄疸。慢性蛲虫病的特点是多种但不太明显的胃肠道症状;全身性中毒较急性中毒少见。变态反应症的临床表现仅在慢性感染患者中观察到，而在急性蛇胸腺病患者中发现了更明显的实验室体征。慢性感染的特点是其他实验室参数的变化不太显著。吡喹酮用于治疗蛇胸腺病。关键词:诊断、临床表现、治疗、阿片吸虫病、急性、慢性、流行病学分析

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来源期刊

Infektsionnye Bolezni Medicine-Infectious Diseases

CiteScore

1.30

自引率

0.00%

发文量

期刊介绍： The journal publishes original research works, reviews of literature, lectures, methodological recommendations, clinical observations. Main topics: problems of etiology, pathogenesis, clinical manifestations of infectious diseases, new techniques and methods of their diagnosis, prevention and treatment; special attention is paid to the problems of antibacterial and antiviral therapy, the use of immunoglobulins and interferons, and also to intensive therapy of critical states. The journal is in the List of leading scientific journals and periodicals of the Supreme Attestation Committee, where the principal results of doctoral dissertations should be published.