Corneal biomechanics and cornea assessment in Fuchs heterochromic iridocyclitis patients

Abstract

Aim: To evaluate cornea and corneal biomechanical properties of patients with Fuchs heterochromic iridocylitis. Materials and Methods: Fourteen FHI positive eyes (Group 1) and the contralateral healthy eyes (Group 2) were included. All patients underwent a detailed ophthalmic examination was performed. Also, Ocular Response Analyzer was used to detect corneal biomechanical properties, and specular microscopic evaluation for corneal endothelial cells count was performed. Results: The mean best corrected visual acuity and intraocular pressure were statistically similar. (p values were 0.077 and 0.557, respectively). Corneal biomechanical properties including corneal hysteresis, corneal resistance factor, IOPcc and IOPg were not statistically significant. (p values were 0.521, 0.817, 0.980 and 0.980, respectively). Mean central corneal thickness in Group 1 and 2 were 555.57±42.95 (467-626), 556.5±37.04 (480-623) micrometer, respectively. The difference was not statistically significant (p=0.959). Mean corneal endothelial cell density of Group 1 and Group 2 were 2313±420.22 (1271-2717) and 2404.42±326.75 (1566-2834) cells/mm2, respectively. The difference was not statistically significant (p=0.626). Conclusion: Conflicting with the literature, no differences were detected in corneal biomechanical properties, central corneal thickness and corneal endothelial cell density in Fuchs Heterochromic Iridocyclitis positive eyes. However, more studies with increasing number of patients are still needed.