Prevalence of lipoprotein lipase mutation in patients with severe hypertriglyceridemia and the characteristic features of hypertriglyceridemic pancreatitis

U. Soyaltin, Ayşe Bengu KANDEMIR BOZKURT, A. Solmaz, Gülden Hakverdi, Ilgın Yıldırım Şımşır
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Abstract

Aim: We conducted a retrospective study with the aim of determining the prevalence of lipoprotein lipase (LPL) mutation in patients with severe hypertriglyceridemia (HTG) and to study differences in characteristic features of HTG induced acute pancreatitis (AP). Materials and Methods: Seventy adults with a serum triglyceride (TG) level ≥500 mg/dL were included in the study. Baseline characteristics, LPL mutation and risk factors between those with and without HTG-AP were compared. Results: The mean age was 43 ± 12 years, and males accounted for 55.7%. Of the patients 35 had TG level
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脂蛋白脂肪酶突变在严重高甘油三酯血症患者中的患病率和高甘油三酯血症性胰腺炎的特征
目的:我们进行了一项回顾性研究,旨在确定严重高甘油三酯血症(HTG)患者中脂蛋白脂肪酶(LPL)突变的患病率,并研究HTG诱导的急性胰腺炎(AP)特征的差异。材料与方法:70例血清甘油三酯(TG)水平≥500 mg/dL的成人纳入研究。比较HTG-AP患者和非HTG-AP患者的基线特征、LPL突变和危险因素。结果:平均年龄43±12岁,男性占55.7%。35例患者有TG水平
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审稿时长
7 weeks
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