Александр Игоревич Медвецкий, Лидия Ильинична Щербакова, Владислав Алексеевич Компанцев, Л. П. Гокжаева, Т. М. Васина
{"title":"ИЗУЧЕНИЕ СТАБИЛЬНОСТИ И УСТАНОВЛЕНИЕ СРОКОВ ГОДНОСТИ МИКРОЧАСТИЦ АЛПРАЗОЛАМА НА ОСНОВЕ ПОЛИ-D,L-ЛАКТИД-КО-ГЛИКОЛИДА","authors":"Александр Игоревич Медвецкий, Лидия Ильинична Щербакова, Владислав Алексеевич Компанцев, Л. П. Гокжаева, Т. М. Васина","doi":"10.19163/2307-9266-2014-2-4(5)-63-70","DOIUrl":null,"url":null,"abstract":"Stability of microparticles of alprazolam in natural conditions was studied by the method of \"accelerated aging\". It was established that microparticles of alprazolam were not exposed to disruption and their appearance was not altered during the research. Expiration dates of alprazolam microparticles determination was calculated using the formula of J.H. van't Hoff. The expiration date made 2 years.","PeriodicalId":40926,"journal":{"name":"Pharmacy & Pharmacology-Farmatsiya i Farmakologiya","volume":"2 1","pages":"63-70"},"PeriodicalIF":0.5000,"publicationDate":"2015-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmacy & Pharmacology-Farmatsiya i Farmakologiya","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.19163/2307-9266-2014-2-4(5)-63-70","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0
Abstract
Stability of microparticles of alprazolam in natural conditions was studied by the method of "accelerated aging". It was established that microparticles of alprazolam were not exposed to disruption and their appearance was not altered during the research. Expiration dates of alprazolam microparticles determination was calculated using the formula of J.H. van't Hoff. The expiration date made 2 years.