Psychiatric Aspects Of MDMA (3,4-Methylenedioxymethamphetamine): The 'Diathesis-Stress' Explanatory Model

A. Parrott
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Abstract

The first individual case studies were published around 1990-1994, soon after MDMA was used for recreational purposes. In a comprehensive review of this case study literature, around one third of individuals had premorbid problems, while most cases did not have prior vulnerability factors [3]. Larger population surveys have found that recreational Ecstasy use is associated with significantly raised levels of depression, anxiety, phobic anxiety, agoraphobia, and paranoid psychosis [4-10]. The occurrence of these problems is associated with lifetime Ecstasy/MDMA usage [4, 5]. Furthermore, around 70% of recreational users report improved psychiatric wellbeing, after quitting ecstasy [6]. Other functional problems in
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MDMA(3,4-亚甲基二氧基甲基苯丙胺)的精神病学方面:“素质-压力”解释模型
第一个个案研究发表于1990-1994年左右,就在MDMA被用于娱乐目的后不久。在对这一案例研究文献的全面回顾中,大约三分之一的个体有发病前问题,而大多数病例没有先前的易感因素bbb。更大规模的人口调查发现,娱乐性的摇头丸使用与抑郁、焦虑、恐惧性焦虑、广场恐怖症和偏执型精神病的水平显著升高有关[4-10]。这些问题的发生与终生使用摇头丸/MDMA有关[4,5]。此外,在戒掉摇头丸之后,大约70%的娱乐使用者报告说他们的精神健康得到了改善。其他功能性问题
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