{"title":"Acute and Long-Term Behavioural Effects of MDMA in Adolescent Rats","authors":"E. Remmelink, I. McGregor","doi":"10.2174/1874941001104010042","DOIUrl":null,"url":null,"abstract":"Acute MDMA, even at low doses, increases social interaction in adult rats [1] while on the long-term its consumption produces a decrease in social interaction, an increase in anxiety and impaired object recognition memory [2, 3]. This study investigated whether MDMA has the same effects in adolescent rats. Additionally, we investigated whether the preference of adolescent rats for MDMA was mediated by social context.","PeriodicalId":89289,"journal":{"name":"The open addiction journal","volume":"4 1","pages":"42-43"},"PeriodicalIF":0.0000,"publicationDate":"2011-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The open addiction journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1874941001104010042","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Acute MDMA, even at low doses, increases social interaction in adult rats [1] while on the long-term its consumption produces a decrease in social interaction, an increase in anxiety and impaired object recognition memory [2, 3]. This study investigated whether MDMA has the same effects in adolescent rats. Additionally, we investigated whether the preference of adolescent rats for MDMA was mediated by social context.
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