Overlap syndrome of juvenile dermatomyositis with systemic lupus erythematosus: A rare case report of diagnostic perplex

Vasudha A. Belgaumkar, Rachana Raj, Shekhar N. Pradhan, Gauri Bhale
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Abstract

Overlap syndromes include a heterogenous group of conditions presenting with mixed features of more than one autoimmune disorder simultaneously in the same patient. Systemic lupus erythematosus (SLE) with myositis overlap is a rare scenario, particularly in the pediatric age group.
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青少年皮肌炎合并系统性红斑狼疮的重叠综合征:一例罕见的诊断难题报告
引言重叠综合征包括一组异质性疾病,在同一患者中同时表现出一种以上自身免疫性疾病的混合特征。系统性红斑狼疮(SLE)合并肌炎重叠是一种罕见的情况,尤其是在儿童年龄组。病例详情我们描述了一名青春期女孩,表现为光敏性、皮肤溃疡、脱发、眶周水肿、近端肌无力和指坏疽。根据重叠的临床特征、实验室标志物如贫血、严重蛋白尿、低补体血症、肌肉酶升高以及抗核抗体、dsDNA和抗Ro/抗SSA阳性,她被诊断为SLE青少年皮肌炎(DM)重叠。及时联合甲基强的松龙环磷酰胺脉冲治疗,疗效显著改善。结论重叠综合征在诊断和治疗方面具有挑战性,其结果不可预测,治疗指南不明确。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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