Ductal Carcinoma in Situ within a Benign Phyllodes Tumor of Breast: Report of a Case

R. Salek, N. S. Sistani, M. Forghani, Mahboobeh Sadeghi Ivari
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Abstract

Introduction: Phyllodes tumor (PT) is not a common phenomenon and its coexistence with ductal carcinoma in situ (DCIS) is extremely rare. A few of these cases have been reported in the literatures. Case Presentation: We report a case of PT that a DCIS tumor has arisen from its epithelial component in a 26 year-old woman. The patient was referred to a surgeon with a palpable mass in her left breast. Ultrasonography failed to distinguish between fibroadenoma and PT. Excisional biopsy was performed for her and after pathologic study, the above - mentioned diagnosis was reported. Histologically stroma showed moderate cellularity with few mitoses. The epithelial component consisted of foci of ductal hyperplasia with comedo necrosis. After consultation with oncologists, simple mastectomy and reconstruction was performed for her. The patient was satisfied with the results. Conclusions: Diagnosis of DCIS within a PT before surgery is impossible and pathologist should confirm it. Different plans for their treatment have had good short term results.
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乳腺良性叶状瘤内导管原位癌1例报告
叶状瘤(Phyllodes tumor, PT)并不常见,与导管原位癌(ductal carcinoma in situ, DCIS)共存极为罕见。文献中已经报道了其中的一些病例。病例介绍:我们报告一个26岁女性的DCIS肿瘤起源于其上皮成分。病人因左乳房有明显肿块而被转诊给外科医生。超声检查未能区分纤维腺瘤和PT。对她进行了切除活检,经病理检查后,报告了上述诊断。组织学上基质呈中等细胞性,有丝分裂少。上皮组织由导管增生灶和粉刺样坏死组成。在咨询了肿瘤学家后,为她进行了简单的乳房切除术和重建。病人对结果很满意。结论:术前在PT内诊断DCIS是不可能的,需经病理证实。不同的治疗方案都有很好的短期效果。
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