Rákos és rákmegelőző állapotok története: szájüregi leukoplakia definíciók és klasszifikációk változása

Abstract

The description of cancers and precancerous disorders goes back to Hippocrates. Each historic age had its own specialities, thus polyhistorians, medical doctors, anatomists and pathologists described diseases and the treatment options according to their own body of knowledge. For a long time, researchers were interested in the development of cancer and its related changes in the human body. Later on, diagnostic and therapeutic solutions came to the fore. Actually, cancer research is a dynamically evolving discipline, development of which is essential, since the conditions are typically incurable, fatal diseases. The importance of precancerous disorders was also highlighted through historic ages. Early diagnosis of these lesions is critical for avoiding potentially developing malignancies. Oral leukoplakia is one of the most common precancerous disorders. In oral precancerous disorders, there are several changes in definitions and terms in the national and international literature as well. The main diagnostic and therapeutic criteria have also changed over the years thanks to the latest discoveries. It is advisable to follow the current literature about accepted definitions and protocols, however, it is useful to study the differences among grouping and individual classifications since these are just calling our attention to diagnostic Kulcsszavak: leukoplakia, dysplasia, rákmegelőző, potenciálisan malignus