Outcome of C-arm Guided Epidural Steroid Injections in Patients with Prolapsed Lumbar Intervertebral Disc with Radiculopathy

Tamjid Ali MD, Moshiur Rahman Khasru, Salek Akm, Alauddin Sikdar, Quazi Tamanna Haque
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Abstract

Background: Prolapsed Lumbar Intervertebral Disc (PLID) is one of the most common health problems worldwide, as well as in our country, and is one of the potential causes of temporary disability, morbidity, and reasoning of absence at workplaces. Objective: To find out the outcome of C-arm guided transforaminal and caudal epidural steroid injection for low back pain with radiculopathy due to PLID. Methodology: This was a randomized clinical trial conducted among purposively selected 54 patients with PLID with radiculopathy as per selection criteria, attending the Department of Physical Medicine & Rehabilitation in BSMMU, Dhaka, from March 2020 to February 2021. Patients (N=54) were randomly allocated into two groups; patients in group A (n=26) were treated with C-arm guided transforaminal and caudal epidural steroid injection with conservative treatment, and patients in group B (n=28) were treated with conservative treatment only. All patients were followed up in 1st week, 1st month, and 3rd month. Results: The mean age of the participants in group A and group B were 40.88 (± 8.70) and 43.00 (± 11.54) years, respectively. In group A, 9 (34.6%) were housewives, 4 (15.4%) were manual workers, while in group B, 10 (35.7%) were housewives, and 8 (28.6%) were manual workers. In group A, 21 (80.8%) had three disc involvement, while in group B, 19 (67.9%) had three discs involvement, where L4-5-disc involvement was most common in both groups. There was no significant statistical difference between the groups regarding VAS scores at baseline (p=0.235), 1st week (p=0.164), and 1st month (p=0.125). The VAS score was significantly reduced in group A compared to group B at 3rd month (p=0.001). The ODI score was significantly reduced in group A compared to group B at 1st week (p=0.034), 1st month (p=0.016), and at 3rd month (p=0.001). Conclusion: C-arm guided transforaminal and caudal Epidural Steroid Injection significantly improves pain and functional outcomes of patients with radiculopathy due to PLID. Long-term, large scale and multicenter research studies are required to establish the outcome and effectiveness of this procedure.
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c臂引导下硬膜外类固醇注射治疗伴有神经根病的腰椎间盘突出症的疗效
背景:腰椎间盘突出症(PLID)是世界范围内最常见的健康问题之一,在我国也是如此,它是导致暂时残疾、发病和缺勤的潜在原因之一。目的:探讨c臂引导下经椎间孔及尾侧硬膜外类固醇注射治疗PLID所致下背部神经根性疼痛的疗效。方法:这是一项随机临床试验,在2020年3月至2021年2月期间,在达卡BSMMU物理医学与康复科有目的地选择54例伴有神经根病的PLID患者进行。54例患者随机分为两组;A组(26例)行c臂引导下经椎间孔及尾侧硬膜外类固醇注射保守治疗,B组(28例)仅行保守治疗。所有患者于第1周、第1个月、第3个月随访。结果:A组和B组患者平均年龄分别为40.88(±8.70)岁和43.00(±11.54)岁。A组家庭主妇9人(34.6%),体力劳动者4人(15.4%),B组家庭主妇10人(35.7%),体力劳动者8人(28.6%)。A组21例(80.8%)有三椎间盘受累,B组19例(67.9%)有三椎间盘受累,其中l4 -5椎间盘受累在两组中最常见。各组VAS评分基线(p=0.235)、第1周(p=0.164)、第1个月(p=0.125)比较,差异均无统计学意义。第3个月时,A组VAS评分明显低于B组(p=0.001)。与B组相比,A组在第1周(p=0.034)、第1个月(p=0.016)和第3个月(p=0.001) ODI评分显著降低。结论:c臂引导下经椎间孔和尾侧硬膜外类固醇注射可显著改善PLID所致神经根病患者的疼痛和功能预后。需要长期、大规模和多中心的研究来确定这一程序的结果和有效性。
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