Crohn’s Disease: A Curable Disease Held Hostage?

G. Monif
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Abstract

(MAP) could be so challenged to abort mycobacterium replication that its inherent immune system became fixed within immunological memory. Owing to the loss of immunological tolerance, every time the baby’s immune system encountered MAP. it would again respond by elaborating pro-inflammatory cytokines directed at MAP at its points of mucosal attachment to the gastrointestinal mucosa and its antigen processing. A major factor complicating attempts to construct meaningful comparative therapeutic groups for clinical trials is the degree to which the gastrointestinal microbiota has
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克罗恩病:一种可治愈的疾病?
(MAP)可能受到如此大的挑战而中止分枝杆菌的复制,以至于其固有的免疫系统在免疫记忆中被固定。由于免疫耐受性的丧失,每次宝宝的免疫系统都会遇到MAP。它会再次作出反应,在MAP与胃肠道粘膜的黏附点及其抗原加工处,产生促炎细胞因子。为临床试验构建有意义的比较治疗组的一个主要因素是胃肠道微生物群的变化程度
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