Ethno-Medicinal and Therapeutic Applications of Natural Anthraquinones: Recent Trends and Advancements

IF 0.4 4区 医学 Q4 PHARMACOLOGY & PHARMACY Indian Journal of Pharmaceutical Sciences Pub Date : 2023-01-01 DOI:10.36468/pharmaceutical-sciences.1122
M. Mohapatra, U. Basak
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Abstract

Pharmacological Uses of Certain Anthraquinones Traditional and ethno-medicinal use of plants enforces a holistic approach towards human health by wittily utilizing the synergistic potency of the bioactive compounds. Quinones are unique molecules with several therapeutic properties that lead them as most vital compound in pharmaceutical system. They can easily undergo reduction reaction paving the path for many biological processing. This class of molecules helps in treatment of several chronic ailments. Many of the drugs in Ayurvedic formulations and/or modern medicinal sectors are having one or more types of quinone groups as a major bio-active compound. However these aforementioned properties of quinones make them unique and versatile. The biochemical knowledge of these compounds is necessary to understand their physiological and toxicological properties. Amongst all quinones found naturally, anthraquinones are one of its kinds due to wide spectrum utilization in several drug formulations. In this review a brief detail of six unique yet ethno-botanically and pharmacologically versatile quinone compounds are depicted with their natural resources, structural characterization and ethno-pharmacological activities. The gathered information regarding the above mentioned bio-active compounds would be helpful in identification and isolation of these compounds from a wide range of natural sources with structural characterization and pharmacological potency. These data would be pivotal in their precise identification for further use in both Ayurvedic and modern drug formulation sectors thereby lessening the threat status of the frequently used rare, endangered and threatened plants.
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天然蒽醌的民族医药和治疗应用:最新趋势和进展
某些蒽醌类药物的药理用途植物的传统和民族医学用途通过巧妙地利用生物活性化合物的协同效力,强制采用一种全面的方法来保护人类健康。醌是一种独特的分子,具有多种治疗特性,是药物系统中最重要的化合物。它们很容易发生还原反应,为许多生物处理铺平了道路。这类分子有助于治疗几种慢性疾病。阿育吠陀配方和/或现代医药部门的许多药物都含有一种或多种醌类,作为主要的生物活性化合物。然而,上述醌类的性质使它们独特而多功能。了解这些化合物的生化知识对于了解它们的生理和毒理学特性是必要的。在所有天然发现的醌类中,蒽醌类是其中一种,因为它在几种药物配方中具有广泛的光谱利用。本文简要介绍了六种独特的民族植物学和药理学上通用的醌类化合物的天然资源、结构特征和民族药理学活性。所收集的有关上述生物活性化合物的信息将有助于从广泛的天然来源中鉴定和分离这些具有结构表征和药理学效力的化合物。这些数据对于在阿育吠陀和现代药物配方部门进一步使用它们的精确识别至关重要,从而减少经常使用的稀有、濒危和受威胁植物的威胁状况。
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期刊介绍: The Indian Journal of Pharmaceutical Sciences (IJPS) is a bi-monthly Journal, which publishes original research work that contributes significantly to further the scientific knowledge in Pharmaceutical Sciences (Pharmaceutical Technology, Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy and Phytochemistry, Pharmacology and Therapeutics, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Pharmacovigilance, Pharmacoepidemiology, Pharmacoeconomics, Drug Information, Patient Counselling, Adverse Drug Reactions Monitoring, Medication Errors, Medication Optimization, Medication Therapy Management, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest). The Journal publishes original research work either as a Full Research Paper or as a Short Communication. Review Articles on current topics in Pharmaceutical Sciences are also considered for publication by the Journal.
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