Endoscopic submucosal dissection for colorectal lesions in elderly patients

Abstract

Objective To investigate the safety and effectiveness of endoscopic submucosal dissection(ESD) for elderly patients(≥60 years old) with colorectal lesions. Methods Data of 31 elderly patients(≥60 years old) and 23 non-elderly(<60 years old) patients who were found to have colorectal mucosal lesions by colonoscopy and underwent ESD treatment between January 2012 to January 2014 were retrospectively studied. Results There were no statistical differences between the two groups in gender, concomitant diseases, lesion location, lesion size and postoperative pathological diagnosis(P>0.05). Thirty-two lesions in elderly group and twenty-five lesions in non-elderly group were all curative resection. En bloc resection rates were 96.9%(31/32)and 96.0%(24/25)in the elderly group and non-elderly group respectively; the rates of bleeding during ESD procedure were 3.2%(1/31)and 4.3%(1/23); delayed bleeding rates were 12.9%(4/31)and 13.0%(3/23); the rates of perforation was 12.9%(4/31)and 0; postoperative infection rates were 3.2%(1/31) and 4.3%(1/23) respectively. There were no statistical differences between the two groups in any of these data(P>0.05). The mean time of follow-up were(14.8±1.7)months in elderly group and(14.7±1.8)months in non-elderly group, and there was no significant difference between two groups. No residual lesion or recurrent lesion was found in the follow-up period. Conclusion ESD is a safe and effective treatment for the elderly patients with colorectal lesion. Key words: Aged; Endoscopic submucosal dissection; Colorectum