Two Cases of Hemifacial Spasm Completely Recovered after Repeated BTX-A Treatment

T. Shen, Yingying Xu, Jing-Liu, W. Luo, Xia Zhang
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Abstract

Hemifacial Spasm (HSF) refers to the intermittently involuntary clonic twitch or painless rigidity of one or two sides of facial muscles. Patients with hemifacial spasm generally have a decline in quality of life, accompanied by anxiety, depression and other emotional problems, which further aggravate hemifacial spasm symptoms. BTX-A injection is the first choice for treatment of HFS, which can not only relief the symptoms of HFS but also improve the mood problems. There have been no reported cases of HFS cured by drugs or BTX-A. Here we reported two HFS patients recovered after multiple BTX-A treatments without recurrence for 3-8 years, which might provide a clue for further exploration of the pathogenesis of HFS.
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反复BTX-A治疗面肌痉挛完全恢复2例
面肌痉挛是指面肌一侧或两侧的间歇性不自觉的阵挛性抽搐或无痛性强直。面肌痉挛患者一般生活质量下降,伴有焦虑、抑郁等情绪问题,进一步加重面肌痉挛症状。BTX-A注射液是治疗HFS的首选药物,不仅可以缓解HFS的症状,还可以改善患者的情绪问题。目前还没有HFS通过药物或BTX-A治愈的病例报告。本研究报告2例HFS患者经多次BTX-A治疗后3-8年无复发,可能为进一步探讨HFS的发病机制提供线索。
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