Noorhayati Binti Mohamad Nadzir, P. Raman, S. PremalaDevi, Khairul Husnaini Mohd Khalid
{"title":"Miller Fisher Syndrome Variant: The Incomplete Triad","authors":"Noorhayati Binti Mohamad Nadzir, P. Raman, S. PremalaDevi, Khairul Husnaini Mohd Khalid","doi":"10.37421/2165-7920.2021.11.1454","DOIUrl":null,"url":null,"abstract":"Miller Fisher Syndrome (MFS) is a rare inflammatory peripheral neuropathy where the diagnosis is made based on the clinical triad of ophthalmoplegia, ataxia, and areflexia. It is considered a variant of Guillain-Barre Syndrome (GBS) and associated with antiGQ1b IgG positive serology. Reports on cerebellar ataxia and supranuclear gaze palsy in MFS suggested an additional involvement of the central nervous system, encompassing Bickerstaff's Brainstem Encephalitis (BBE) spectrum.","PeriodicalId":73664,"journal":{"name":"Journal of clinical case reports","volume":"11 1","pages":"1-2"},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of clinical case reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37421/2165-7920.2021.11.1454","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Miller Fisher Syndrome (MFS) is a rare inflammatory peripheral neuropathy where the diagnosis is made based on the clinical triad of ophthalmoplegia, ataxia, and areflexia. It is considered a variant of Guillain-Barre Syndrome (GBS) and associated with antiGQ1b IgG positive serology. Reports on cerebellar ataxia and supranuclear gaze palsy in MFS suggested an additional involvement of the central nervous system, encompassing Bickerstaff's Brainstem Encephalitis (BBE) spectrum.
Miller Fisher综合征(MFS)是一种罕见的炎性周围神经病变，其诊断基于眼麻痹、共济失调和反射性松弛的临床三联征。它被认为是格林-巴利综合征(GBS)的一种变体，与抗gq1b IgG血清学阳性相关。关于MFS患者小脑共济失调和核上凝视性麻痹的报道表明，中枢神经系统还受影响，包括比克斯塔夫脑干脑炎(BBE)谱。
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