Nonalcoholic fatty liver disease and metabolic syndrome

G. Xi
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Abstract

Nonalcoholic fatty liver disease(NAFLD)comprises a disease spectrum which includes variable degrees of simple steatosis nonalcoholic steatohepatitis(NASH) and cirrhosis even liver failure and patocellular carcinoma.NAFLD can be considered the hepatic manifestation of the metabolic syndrome and is an independent predictor of type 2 diabetes(T2DM) and cardiovascular disease(CVD).Insulin resistance is the pathogenetic link between the metabolic syndrome and fat accumulation in the liver.Patients with NAFLD are a high risk population of the both of diseases.It's very important significance to early diagnosis and treatment of NAFLD for prevention T2DM and CVD.
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非酒精性脂肪性肝病和代谢综合征
非酒精性脂肪性肝病(NAFLD)包括一系列疾病,包括不同程度的单纯性脂肪变性、非酒精性脂肪性肝炎(NASH)和肝硬化,甚至肝衰竭和肝细胞癌。NAFLD可以被认为是代谢综合征的肝脏表现,是2型糖尿病(T2DM)和心血管疾病(CVD)的独立预测因子。胰岛素抵抗是代谢综合征与肝脏脂肪堆积之间的病理联系。NAFLD患者是两种疾病的高危人群。早期诊断和治疗NAFLD对预防T2DM和CVD具有十分重要的意义。
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