Pestivirus Species Potential Adventitious Contaminants of Biological Products

M. Giangaspero
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引用次数: 16

Abstract

Bovine Viral Diarrhea virus species of the genus Pestivirus, important pathogens affecting zootechnics worldwide, have been reported as adventitious contaminants of biological products for veterinary and human use. The Bovine Viral Diarrhea virus 1 species showed potential for an emerging zoonosis. According to World Organization for Animal Health (Office International des Epizooties: OIE), Bovine Viral Diarrhea is a notifiable disease of importance to international trade. Recently, Bovine Viral Diarrhea virus 3 tentative species have been isolated from Brazil and Thailand. The virus has been diffused from South America to other countries probably through the commercialization of contaminated fetal bovine serum.
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生物制品的潜在外来污染物鼠疫病毒种类
牛病毒性腹泻病毒是影响世界范围内动物技术的重要病原体,已被报道为兽药和人用生物制品的外来污染物。牛病毒性腹泻病毒1种有可能成为一种新出现的人畜共患病。根据世界动物卫生组织(国际兽疫局:OIE),牛病毒性腹泻是一种对国际贸易具有重要意义的法定报告疾病。最近在巴西和泰国分离到牛病毒性腹泻病毒3型暂定种。该病毒已从南美扩散到其他国家,可能是通过受污染的胎牛血清的商业化。
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