Multiple Symmetrical Lipomatosis in a 67-Year Old African Male: First Case Report within a Resource-Limited Setting

V. Suttels, T. Venter, M. White
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Abstract

Introduction: Multiple Symmetrical Lipomatosis (MSL) is a progressive disease presenting with symmetrically distributed (large) lipomata over the occiput, head, neck, shoulders and trunk resulting in gross deformity. Over 90% of cases are associated with chronic alcohol abuse, and associations with metabolic disorders are also common but malignancy is rare. To date there is only one report of MSL in an African-American patient and no reported cases in Africa. Case Presentation: We report the case of a 67-year old African male with a history of gout and chronic heavy drinking presenting with typical features of multiple symmetrical lipomatosis. The lipomata were successfully removed by a visiting surgical mission team. Discussion: Exact pathogenesis and incidence of MSL remain unclear. Misdiagnosis is common and diagnosis in resource-limited settings should be prompted by the history of alcohol abuse and characteristic presenting features of multiple symmetrical lipomatosis. Challenges of surgical interventions in low-resource settings are discussed. Conclusion: Clinicians should be aware of the condition and its association with metabolic disorders and rarely malignancy. In resource-limited settings, ethical and cultural factors should be considered before proceeding to surgery.
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67岁非洲男性多发对称脂肪瘤:资源有限地区首例报告
简介:多发性对称脂肪瘤病(Multiple symmetric Lipomatosis, MSL)是一种进行性疾病,表现为枕骨、头部、颈部、肩部和躯干对称分布的(大)脂肪瘤,导致严重畸形。超过90%的病例与慢性酒精滥用有关,与代谢紊乱有关也很常见,但恶性肿瘤很少见。迄今为止,只有一名非洲裔美国患者报告了MSL,非洲没有报告病例。病例介绍:我们报告一个67岁的非洲男性痛风和慢性酗酒的历史表现为典型特征的多重对称脂肪瘤病。一个来访的外科任务小组成功地切除了脂肪瘤。讨论:MSL的确切发病机制和发病率尚不清楚。误诊是常见的,在资源有限的情况下,诊断应根据酒精滥用史和多发对称脂肪瘤病的特征来提示。在低资源设置手术干预的挑战进行了讨论。结论:临床医生应意识到这种情况及其与代谢紊乱和恶性肿瘤的关系。在资源有限的情况下,在进行手术前应考虑伦理和文化因素。
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