Invasion of the Left Atrium by a Squamous Lung Cancer.

J. Macedo
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Abstract

Previously, he had no respiratory symptoms, until the day he came to the emergency room with sudden chest pain, with no irradiation and progressive intensity. A CT thoracic angiogram was performed and showed invasion of the left atrium (Figures 1-4). Bronchoscopy revealed in the right bronchi tree an exophytic mass with superficial vascularization and indirect signs of tumor. Biopsy confirmed a squamous lung cancer with moderate differentiation. Immunohistochemistry testing was performed and was positive for cytokeratin 5 and negative for cytokeratin 7, TTF1 and synaptophysin. This diagnosis wasn’t verified by immune staining for p63. The echocardiogram showed an enlarged left ventricle, diffuse hypo kinesia, left ventricle ejection fraction of 36%, dilatation of the left atrium (32 cm2) and right atrium (27 cm2); a hypo echoic mass was in contact with the left atrium, but without direct invasion.
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鳞状肺癌侵袭左心房。
此前,他没有呼吸道症状,直到他来到急诊室的那天突然胸痛,没有照射和进行性强度。CT胸廓血管造影显示左心房受累(图1-4)。支气管镜检查显示右支气管树一外生性肿块伴浅表血管化及间接肿瘤征象。活检证实为中度分化的鳞状肺癌。免疫组化检测细胞角蛋白5阳性,细胞角蛋白7、TTF1、synaptophysin阴性。p63的免疫染色未证实这一诊断。超声心动图示左心室增大,弥漫性运动障碍,左心室射血分数36%,左心房扩张(32 cm2),右心房扩张(27 cm2);低回声肿块与左心房接触,但没有直接侵犯。
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