Anti-SARS-CoV-2 antibodies important in diagnostics of acute hepatitis in children

Q4 Medicine Pediatria Polska Pub Date : 2023-01-01 DOI:10.5114/polp.2023.125696
M. Pawłowska, J. Moppert, Małgorzata Sobolewska-Pilarczyk
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Abstract

The most common causes of acute hepatitis in children are hepatitis A and autoimmune hepatitis. Hepatitis in the course of Wilson's disease is sporadically registered in adolescents. An increase of activity of aminotransferases both in the course of multisystem inflammatory syndrome in children (MIS-C) and in the course of COVID-19 has been observed. Hepatitis is common in children with MIS-C and is associated with a more severe presentation and persistent elevation of liver function tests. To date, no cases of acute hepatitis in children due to COVID-19 have been reported. We present 2 cases of acute hepatitis in children where the only cause seems to be a previous asymptomatic SARS-CoV-2 infection.Copyright © 2023 Termedia Publishing House Ltd.. All rights reserved.
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抗sars - cov -2抗体在儿童急性肝炎诊断中的重要意义
儿童急性肝炎最常见的病因是甲型肝炎和自身免疫性肝炎。肝豆状核变性过程中的肝炎在青少年中偶有发生。在儿童多系统炎症综合征(MIS-C)和COVID-19过程中观察到转氨酶活性升高。肝炎在患有misc的儿童中很常见,并且与更严重的表现和肝功能检查的持续升高有关。迄今为止,尚未报告因COVID-19引起的儿童急性肝炎病例。我们报告了2例儿童急性肝炎,其中唯一的原因似乎是以前无症状的SARS-CoV-2感染。版权所有©2023 Termedia出版社有限公司版权所有。
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来源期刊
Pediatria Polska
Pediatria Polska Medicine-Pediatrics, Perinatology and Child Health
CiteScore
0.40
自引率
0.00%
发文量
19
期刊介绍: Pediatria Polska - rzetelna wiedza i tradycja. Organ Polskiego Towarzystwa Pediatrycznego. Ukazuje się od 1921 roku, poprzednio w latach 1908-1920 jako Przegląd Pedyatryczny. Drugie obok Otolaryngologii Polskiej najstarsze czasopismo medyczne ukazujące się na polskim rynku. Czasopismo zamieszcza doświadczalne i kliniczne prace oryginalne oraz opisy rzadko występujących i trudnych diagnostycznie przypadków klinicznych. W Pediatrii Polskiej publikowane są także obszerne omówienia poglądowe problemów pediatrycznych oparte na najnowszym piśmiennictwie światowym.
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