Cherifa Mahieddine Cherifa Mahieddine, Said Zerkout Said Zerkout, Sidali Rayane Sidali Rayane, Houssam Boulebd Houssam Boulebd, Affaf Laassami Affaf Laassami, Salah Akkal Salah Akkal
{"title":"Synthesis of Dihydroxamic Acids from Dinitrones, Structural Characterization and Antimicrobial Activities","authors":"Cherifa Mahieddine Cherifa Mahieddine, Said Zerkout Said Zerkout, Sidali Rayane Sidali Rayane, Houssam Boulebd Houssam Boulebd, Affaf Laassami Affaf Laassami, Salah Akkal Salah Akkal","doi":"10.52568/001004/jcsp/44.02.2022","DOIUrl":null,"url":null,"abstract":"The benefits of dinitrones (N,Nand#39;-Diphenyl-2,5-thenylenedinitrone, N,Nand#39;-Dimethyl-1,4-phenylenedinitrone and N,Nand#39;-Dibenzyl-1,4-phenylenedinitrone) in the synthesis were chosen as simple process for synthesis of the purified dihydroxamic acid compounds in a shorter time with a good yield and high purity without need to purification. The most stable conformers of the synthesized compounds and their electronic properties have been determined using DFT/B3LYP calculations. Antimicrobial activity assessment of dihydroxamic acids showed their good efficiency.","PeriodicalId":17253,"journal":{"name":"Journal of the chemical society of pakistan","volume":null,"pages":null},"PeriodicalIF":0.6000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the chemical society of pakistan","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.52568/001004/jcsp/44.02.2022","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
The benefits of dinitrones (N,Nand#39;-Diphenyl-2,5-thenylenedinitrone, N,Nand#39;-Dimethyl-1,4-phenylenedinitrone and N,Nand#39;-Dibenzyl-1,4-phenylenedinitrone) in the synthesis were chosen as simple process for synthesis of the purified dihydroxamic acid compounds in a shorter time with a good yield and high purity without need to purification. The most stable conformers of the synthesized compounds and their electronic properties have been determined using DFT/B3LYP calculations. Antimicrobial activity assessment of dihydroxamic acids showed their good efficiency.
期刊介绍:
This journal covers different research areas in the field of Chemistry. These include; Analytical Chemistry, Applied Chemistry, Biochemistry, Environmental Chemistry, Industrial Chemistry, Inorganic Chemistry, Organic Chemistry and Physical Chemistry. The journal publishes full length articles and Reviews from researchers in academia in addition to featuring comments. Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry.