A Historical Analysis of the Quest for the Origins of Aging Macula Disorder, the Tissues Involved, and Its Terminology.

P. Jong
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引用次数: 16

Abstract

Although ocular tissues involved in aging macula disorder (AMD) were already known in 300 BC, the last type of photoreceptors was discovered only 10 years ago. The earliest descriptions of AMD appeared around 1850. It took over 150 years, till a clearer concept of AMD was formulated and even longer to grasp its pathophysiology. The uncertainty of researchers about the pathogenesis of AMD over the last century is reflected in its changing terminology. The evolution of this terminology is provided in a table to afford the reader a better insight into explanations proposed by researchers during this quest.
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对老年性黄斑病变起源、相关组织及其术语的历史分析。
虽然早在公元前300年人们就已经知道与衰老性黄斑病变(AMD)有关的眼部组织,但最后一种光感受器直到10年前才被发现。AMD最早的描述出现在1850年左右。人们花了150多年的时间才对AMD有了更清晰的概念,而对其病理生理学的掌握则更久。上个世纪研究者对AMD发病机制的不确定性反映在其不断变化的术语上。这个术语的演变在一个表格中提供,以便读者更好地了解研究人员在这一探索过程中提出的解释。
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