Aspergillus hip arthritis in COVID-19 era: Two case reports

R. Mukartihal, Rajdeep Das, Bharath Krishna, S. Patil
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Abstract

Corticosteroids have been a mainstay in the treatment protocols and guidelines of COVID-19. However, its use in high dosage or for extended duration renders patients immunocompromised after COVID-19 recovery, and thus, susceptible to secondary opportunistic infections. We report the two cases of septic hip arthritis due to Aspergillus species in corticosteroid immunosuppressed post-COVID-19 patients. One patient recovered successfully from the arthritis and subsequently underwent total hip arthroplasty with good outcome. The second patient presented late to us in a critical condition and had two comorbid conditions along with, due to which, in spite of all measures, could not be revived and succumbed to death. We highlight the issue of the rare cause of fungal hip arthritis in immunosuppressed post-COVID-19 patients and stress the necessity to remain vigilant and identify the causative organisms correctly, especially fungal pathogens in such susceptible populations in the present COVID-19 era.
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新冠肺炎时代曲霉菌性髋关节关节炎2例报告
皮质类固醇一直是COVID-19治疗方案和指南的主要内容。然而,大剂量或长时间使用该药物会使患者在COVID-19康复后免疫功能低下,从而容易发生继发性机会感染。我们报告了两例由曲霉菌引起的皮质类固醇免疫抑制的covid -19后患者脓毒性髋关节关节炎。一名患者成功地从关节炎中恢复,随后接受了全髋关节置换术,结果良好。第二例患者在病情危重的情况下就诊较晚,并伴有两种合并症,尽管采取了各种措施,但仍无法复苏,最终死亡。我们强调在COVID-19后免疫抑制患者中真菌性髋关节关节炎的罕见病因问题,并强调在当前COVID-19时代,在这些易感人群中保持警惕并正确识别病原生物,特别是真菌病原体的必要性。
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来源期刊
Journal of Arthroscopy and Joint Surgery
Journal of Arthroscopy and Joint Surgery Medicine-Orthopedics and Sports Medicine
CiteScore
0.60
自引率
0.00%
发文量
1
期刊介绍: Journal of Arthroscopy and Joint Surgery (JAJS) is committed to bring forth scientific manuscripts in the form of original research articles, current concept reviews, meta-analyses, case reports and letters to the editor. The focus of the Journal is to present wide-ranging, multi-disciplinary perspectives on the problems of the joints that are amenable with Arthroscopy and Arthroplasty. Though Arthroscopy and Arthroplasty entail surgical procedures, the Journal shall not restrict itself to these purely surgical procedures and will also encompass pharmacological, rehabilitative and physical measures that can prevent or postpone the execution of a surgical procedure. The Journal will also publish scientific research related to tissues other than joints that would ultimately have an effect on the joint function.
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