An unusual case of coronavirus disease 2019 associated with chronic myeloid leukemia in a young male presenting with priapism

B. Iqbal, Prtyush Mishra, Rakesh Kumar
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Abstract

Patients with chronic myeloid leukemia (CML) usually present in the elderly age and rarely in the adolescents and young adults (AYA) groups. In this case report, we describe a case of a 28-year-old male who presented to the hospital with priapism and pain abdomen along with a positive history of coronavirus disease 2019 (COVID-19) disease. The patient was diagnosed as CML based on his peripheral blood smear and bone marrow aspiration findings. These findings were confirmed by fluorescence in situ hybridization (FISH) which showed the presence of breakpoint cluster region/ABL1 fusion gene. The patient was treated with tyrosine kinase inhibitor along with surgical shunt for priapism which showed clinical improvement. There is a very limited understanding of disease management and survival outcomes in this group of patients;therefore, the aim of this case report is to understand the association of COVID-19 infection in patients of AYA group suffering from CML. © 2022 Journal of Medical Society ;Published by Wolters Kluwer - Medknow.
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2019冠状病毒病与慢性髓性白血病的罕见病例,一名年轻男性表现为阴茎勃起
慢性髓性白血病(CML)患者通常出现在老年,很少在青少年和青壮年(AYA)组。在本病例报告中,我们描述了一个28岁的男性病例,他以阴茎勃起和腹部疼痛以及冠状病毒病2019 (COVID-19)疾病的阳性病史来医院就诊。根据他的外周血涂片和骨髓穿刺结果诊断为慢性粒细胞白血病。这些发现被荧光原位杂交(FISH)证实,断点簇区/ABL1融合基因的存在。应用酪氨酸激酶抑制剂联合手术分流治疗阴茎勃起障碍,临床效果明显改善。对这组患者的疾病管理和生存结局的了解非常有限,因此,本病例报告的目的是了解AYA组CML患者中COVID-19感染的相关性。©2022 Medical Society Journal;由Wolters Kluwer - Medknow出版。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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JMS - Journal of Medical Society
JMS - Journal of Medical Society Medicine-Medicine (all)
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