Synchronous Superficial Myofibroblastoma and Stromal polyp of the Vagina: Report of A Case Supporting Common Histogenesis of Both Lesions

M. Zamecnik, Roman Sucansky
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Abstract

Rare simultaneous occurrence of vaginal superficial cervicovaginal myofibroblastoma and vaginal stromal polyp is described. The lesions were found in a 90-years-old patient, in the anterior wall of the vagina. The diameter of the lesions was 6cm and 2cm, respectively. Between them, a 3cm part of normal appearing vaginal wall was present. Both lesions showed similar myoid appearing morphology and myofibroblastic desmin+/actin-/h-caldesmon-/CD34- immunophenotype, with positivity for CD10, CD99, estrogen receptor and progesterone receptor. Larger lesion was diagnosed as benign cervicovaginal myofibroblastoma, and the smaller one had typical features of vaginal stromal polyp. This case of simultaneous occurrence of cervicovaginal myofibroblastoma and vaginal stromal polyp supports previously suggested histogenetic relationship between these lesions.
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阴道同步浅表性肌纤维母细胞瘤和间质息肉:一例支持两种病变共同组织发生的报告
罕见的同时发生阴道浅颈阴道肌纤维母细胞瘤和阴道间质息肉。病变是在一个90岁的病人身上发现的,在阴道前壁。病变直径分别为6cm和2cm。在它们之间,存在正常阴道壁的3cm部分。两种病变均表现出相似的肌样形态和肌成纤维细胞desmin+/actin-/h-caldesmon-/CD34-免疫表型,CD10、CD99、雌激素受体和孕激素受体阳性。较大的病变诊断为良性宫颈阴道肌成纤维细胞瘤,较小的病变具有阴道间质息肉的典型特征。本病例同时发生的宫颈阴道肌成纤维细胞瘤和阴道间质息肉支持先前提出的组织发生关系的病变。
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